Results 151 to 160 of about 3,816 (187)

The dual guardians of cellular stability: exploring nesprin and lamin in senescence. [PDF]

Cell Death Dis
Zhou ZY, Qin Q, Dong C, Liu Y, Cao C, Teng L.   +5 more
europepmc   +1 more source

One week of exposure to sunlight induces progerin expression in human skin

Advances in Dermatology and Allergology, 2017
Lesiak, Aleksandra, Bednarski, Igor, Rogowski-Tylman, Michał, Sobjanek, Michał, Woźniacka, Anna, Danilewicz, Marian, Young, Anthony, Narbutt, Joanna   +7 more
openaire   +2 more sources

A noncanonical cGAS-STING pathway drives cellular and organismal aging. [PDF]

Proc Natl Acad Sci U S A
Cancado de Faria R, Silva LND, Teodoro-Castro B, McCommis KS, Shashkova EV, Gonzalo S.   +5 more
europepmc   +1 more source

Involvement of NRF2 and AMPK signaling in aging and progeria: a digest. [PDF]

Redox Biol
Petsouki E, Gerakopoulos V, Gianniou DD, Heiss EH, Trougakos IP.   +4 more
europepmc   +1 more source

Mitotic dynamics of the nuclear lamina in the backstage of chromosome separation. [PDF]

Commun Biol
Picotto J, Bertrand P, Pennarun G.
europepmc   +1 more source

Loss of A-type lamins and genomic instability [PDF]

, 2009
Gonzalez-Suarez, Ignacio, Gonzalo, Susana, Redwood, Abena B   +2 more
core   +2 more sources

National survey of Hutchinson-Gilford progeria syndrome and progeroid laminopathy in Japan. [PDF]

Aging (Albany NY)
Okawa Y, Matsuo M, Kosaki R, Tonoki H, Fujimoto M, Ozono K, Saitou H, Kubota T, Ohata Y, Namba N, Akaboshi S, Komaki H, Inagaki N, Kato E, Maruo Y, Yonekawa T, Nakamura T, Hayashi K, Miwa S, Magota M, Ihara K.   +20 more
europepmc   +1 more source

Experimental Confirmation of Progerin–Small Peptide Interaction Using NanoLuc Binary Technology Assay in Human Cell Lines to Validate in Silico–Designed Progerin Interactors

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder characterized by accelerated aging, primarily caused by the accumulation of a mutant form of lamin A known as progerin. One of the hallmarks of HGPS is increased oxidative stress, often associated with elevated levels of reactive oxygen species (ROS). In this study, we employed flow
openaire   +1 more source

Lonafarnib Clinical Trials Demonstrate Uncoupling of the Muscle-Bone Unit in Hutchinson-Gilford Progeria Syndrome. [PDF]

J Bone Miner Res
Kreienkamp RJ, Gordon LB, Ehrbar R, Pendleton A, Schiferl DJ, Lyass A, Kleinman ME, Snyder BD, Gordon CM.   +8 more
europepmc   +1 more source

Progerin mRNA Is Associated with Smoking and Signs of Increased Microvascular Damage in Patients with Diabetic Macular Edema. [PDF]

Int J Mol Sci
Zaruba MM, Angermann R, Staggl S, Jeyakumar V, Mair S, Stöckl V, Neyer J, Maurer T, Ungericht M, Gavranovic-Novakovic J, Bauer A, Zehetner C, Messner M.   +12 more
europepmc   +1 more source