A combination of both proteomic and genetic approach to indentify de-regulated pathway in progeria, an accelerated aging disorder [PDF]
Comunicaciones a ...
Arufe, M.C. +8 more
core
Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases [PDF]
core +1 more source
A comprehensive resource for induced pluripotent stem cells from patients with primary tauopathies [PDF]
Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments.
Cairns, Nigel J +7 more
core +1 more source
LAV-BPIFB4 reverses progeria-associated cardiac aging by restoring diastolic function and reducing senescence. [PDF]
Chae U +4 more
europepmc +1 more source
Why and How Are Infants with Hutchinson-Gilford Progeria Syndrome Born Without Severe Manifestations? [PDF]
Erokhina MA +3 more
europepmc +1 more source
Epidural hematoma in a pediatric patient with Hutchinson-Gilford progeria syndrome: management considerations: a case report. [PDF]
Ozmarasali AI, Sivas ZZ, Uguz I, Oto A.
europepmc +1 more source
Hutchinson-Gilford progeria syndrome alters the endothelial genetic response to laminar shear stress. [PDF]
Kennedy CC, Carter JL, Truskey GA.
europepmc +1 more source
Elevated SUN1 promotes migratory cell polarity defects through mechanically coupling microtubules to the nuclear lamina. [PDF]
Li Y +7 more
europepmc +1 more source
Progerin regulates actin cytoskeletal remodeling and inhibits EMT and metastasis in triple‑negative breast cancer cells. [PDF]
Huang X, Luo W, Liu W, Liu X, Chen W.
europepmc +1 more source
A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites. [PDF]
Odell J, Nedza K, Lammerding J.
europepmc +1 more source

