Results 41 to 50 of about 54,878 (125)
Frontiers in Oncology, 2021 ObjectiveThe present study used the RNA sequencing (RNA-seq) dataset to identify prognostic snoRNAs and construct a prognostic signature of The Cancer Genome Atla (TCGA) lower grade glioma (LGG) cohort, and comprehensive analysis of this signature ...
Teng Deng +6 more
doaj +1 more source
Analysis of Genomic and Transcriptomic Variations as Prognostic Signature for Lung Adenocarcinoma [PDF]
, 2019 Lung cancer is the leading cause of the largest number of deaths worldwide and lung adenocarcinoma (LUAD) is the most common form of lung cancer. In this study, we carried out an integrated meta-analysis of the mutations including single-nucleotide variations (SNVs), the copy number variations (CNVs), RNA-seq and clinical data of patients with LUAD ...
arxiv +1 more source
BMC Cancer, 2021 Background This study aimed to develop a reliable immune signature based on B-cell proportion to predict the prognosis and benefit of immunotherapy in LUAD.
Yi Zhang +12 more
doaj +1 more source
Synthesizing Bidirectional Temporal States of Knee Osteoarthritis Radiographs with Cycle-Consistent Generative Adversarial Neural Networks [PDF]
arXiv, 2023 Knee Osteoarthritis (KOA), a leading cause of disability worldwide, is challenging to detect early due to subtle radiographic indicators. Diverse, extensive datasets are needed but are challenging to compile because of privacy, data collection limitations, and the progressive nature of KOA.
arxiv
Quantum attacks on Bitcoin, and how to protect against them [PDF]
Ledger, [S.l.], v. 3, oct. 2018, 2017 The key cryptographic protocols used to secure the internet and financial transactions of today are all susceptible to attack by the development of a sufficiently large quantum computer. One particular area at risk are cryptocurrencies, a market currently worth over 150 billion USD.
arxiv +1 more source
A novel immune-related gene signature predicts the prognosis of hepatocellular carcinoma
Frontiers in Oncology, 2022 Immune-related genes play a key role in regulating the cancer immune microenvironment, influencing the overall survival of patients with hepatocellular carcinoma (HCC).
Shujiao He +3 more
doaj +1 more source
Permutation-Invariant Subgraph Discovery [PDF]
arXiv, 2021 We introduce Permutation and Structured Perturbation Inference (PSPI), a new problem formulation that abstracts many graph matching tasks that arise in systems biology. PSPI can be viewed as a robust formulation of the permutation inference or graph matching, where the objective is to find a permutation between two graphs under the assumption that a ...
arxiv
Finding Reproducible and Prognostic Radiomic Features in Variable Slice Thickness Contrast Enhanced CT of Colorectal Liver Metastases [PDF]
Machine.Learning.for.Biomedical.Imaging. 2 (2025)Establishing the reproducibility of radiomic signatures is a critical step in the path to clinical adoption of quantitative imaging biomarkers; however, radiomic signatures must also be meaningfully related to an outcome of clinical importance to be of value for personalized medicine.
arxiv +1 more source
Frontiers in Cell and Developmental Biology, 2021 RNA binding proteins (RBPs) have been reported to be involved in cancer malignancy but related functions in glioma have been less studied. Herein, we screened 14 prognostic RBP genes and constructed a risk signature to predict the prognosis of glioma ...
Zewei Tu +13 more
doaj +1 more source
Implementation of a geometrically and energetically constrained mesoscale eddy parameterization in an ocean circulation model [PDF]
, 2018 The global stratification and circulation of the ocean and their sensitivities to changes in forcing depend crucially on the representation of the mesoscale eddy field. Here, a geometrically informed and energetically constrained parameterization framework for mesoscale eddies --- termed GEOMETRIC --- is proposed and implemented in three-dimensional ...
arxiv +1 more source