Results 71 to 80 of about 24,430,487 (196)

Investigation of HER2 I655V and PHB 3′UTR C > T polymorphisms in azoospermic infertile males

Egyptian Journal of Medical Human Genetics, 2023
Background Male infertility is a complex, multifactorial pathological condition with a highly heterogeneous phenotypic variation, from complete absence of spermatozoa in the testicles (azoospermia) to marked changes in sperm quality.
Irem Yildiz, Nevin Karakus, Fikret Erdemir   +2 more
doaj   +1 more source

Detection of Ring Structure and Its Flexibility in Periplasmic Region of FliL, Bacterial Flagellar Stator‐Associate Protein, in Marine Vibrio

Molecular Microbiology, EarlyView.
FliL, a single‐pass transmembrane flagellar protein with a large periplasmic domain, associates with the basal body and supports motor function under high‐load conditions (e.g., viscous environments). The periplasmic domain of deletion mutant FliL forms a flexible ring structure, likely reflecting the capacity of the full‐length protein to adaptively ...
Tatsuro Nishikino, Norihiro Takekawa, Raymond Burton‐Smith, Yuki Tajimi, Kazuyoshi Murata, Takayuki Uchihashi, Seiji Kojima, Katsumi Imada, Michio Homma   +8 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Genetic dissection of southern corn leaf blight resistance in sweet corn through genome‐wide association studies and genomic selection

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Southern corn leaf blight (SCLB) is caused by the fungal pathogen Bipolaris maydis (syn. Cochliobolus heterostrophus Drechsler) and is a common disease of fall crops of sweet corn. Phenotyping for SCLB resistance is performed through visual scoring, which is subjective and may limit genetic gain for this quantitative trait.
Darlon V. Lantican, Juan M. Gonzalez, Marco Antonio Peixoto, Kristen A. Leach, Larissa Carvalho Ferreira, Vitor A. Silva de Moura, Katia V. Xavier, Peter Balint‐Kurti, William Tracy, Marcio F. R. Resende Jr.   +9 more
wiley   +1 more source

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise‐Induced Redox Responses in Human Skeletal Muscle

Aging Cell, Volume 25, Issue 9, September 2026.
Findings from this study suggest that aging is accompanied by altered skeletal muscle mitochondrial redox regulation and exercise responsiveness, with decreased mtDNA copy number, increased mtDNA mutation deletion frequency, and selective redox remodeling of key mitochondrial proteins representing potential contributors to these changes. ABSTRACT Redox
Bradley A. Ruple, Nicholas A. Carlini, Jason S. Kofoed, Helya Rostamkhani, Brady E. Hanson, Jesse C. Craig, Shelby C. Osburn, Allison M. Manuel, Paul A. Stewart, Jonathan Wanagat, Ryan M. Broxterman, Joel D. Trinity   +11 more
wiley   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids [PDF]

, 2023
BACKGROUND AND AIMS: IgG4-related cholangitis (IRC) is the hepatobiliary manifestation of IgG4-related disease, a systemic B cell-driven fibro-inflammatory disorder.
Trampert, David C, Vos, Harmjan R, Beuers, Ulrich, Kersten, Remco, Tolenaars, Dagmar, Hubers, Lowiek M, van de Graaf, Stan F J   +6 more
core  

Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles

Traffic, Volume 27, Issue 3, September 2026.
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto, Amir Fardin, Matteo Balestra, Pier Paolo Di Fiore, Chiara Tordonato, Sara Sigismund   +5 more
wiley   +1 more source

Prohibitin – At the crossroads of obesity-linked diabetes and cancer

, 2017
The promoter of a gene that is selectively expressed in just a few cell types provides unique opportunities to study: (1) the pleiotropic function of a protein in two different cell types including the cell compartment specific function, and (2) the ...
Suresh Mishra, BL Grégoire Nyomba
core   +1 more source

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source