Results 51 to 60 of about 24,430,487 (196)

Coverage of female-specific and unisex variants of prohibitin-2 and ksr2 in female and male specific libraries.

, 2022
The reads of the female (pink) and male (blue) library from one egg string were mapped against the female-specific and unisex variants of the sex-specific genes.
Anna Zofia Komisarczuk (10301145), Frank Nilsen (71512), Andreas Borchel (5373479)   +2 more
core   +1 more source

Prohibitin Proteine: Chaperone der Mitochondrien und Adhäsion

, 2007
Title and Table of contents 1.1. Abstract 7 1.2. Zusammenfassung 8 2\. Introduction 9 3\. Objectives 25 4\. Results 26 5\. Discussion 49 6\. Materials 58 7\. Methods 69 7.1. Cell culture methods 69 7.2. Protein methods 78
Sievers, Claudia
core   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

In situ architecture of the human prohibitin complex [PDF]

Prohibitins are a highly conserved family of proteins that have been implicated in a variety of functions including mitochondrial stress signalling and housekeeping, cell cycle progression, apoptosis, lifespan regulation and many others.
Lange, F., Wenzel, Dirk, Riedel, D., Le Vasseur, M., Jakobs, S, Dohrke, J., Le, Vasseur M, Ratz, M., Ratz, M,, Dohrke, J-N, Riedel, D, Ilgen, P, Riedel, Dietmar, Jakobs, S. ; https://orcid.org/, Dohrke, Jan Niklas, Ilgen, Peter, Dohrke, Jan-Niklas, Ilgen, P., Le Vasseur, Maxence, Wenzel, D., Wenzel, D, Jakobs, Stefan, Lange, Felix, Ratz, Michael, Lange, F   +24 more
core   +1 more source

The prohibitin family of mitochondrial proteins regulate replicative lifespan [PDF]

, 1997
Cellular senescence is determined by multiple factors, including the genetic regulation of metabolism and responses to endogenous and exogenous stresses [1-4]. Recent studies implicate a limited number of gene products in elongating lifespan in yeast and
Prescott, A. R., Jamieson, D.J., Coates, P. J., Jamieson, D. J., Prescott, A.R., Prescott, A. R.; id_orcid, Hall, P.A., Smart, K., Coates, P.J., Hall, P. A.   +9 more
core   +1 more source

Homogenous and Microbeam X-Ray Radiation Induces Proteomic Changes in the Brains of Irradiated Rats and in the Brains of Nonirradiated Cage Mate Rats

Dose-Response, 2018
To evaluate microbeam radiation therapy (MRT), for brain tumor treatment, the bystander effect in nonirradiated companion animals was investigated.
Richard Smith, Jiaxi Wang, Colin Seymour, Cristian Fernandez-Palomo, Jennifer Fazzari, Elisabeth Schültke, Elke Bräuer-Krisch, Jean Laissue, Christian Schroll, Carmel Mothersill   +9 more
doaj   +1 more source

Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases

Cells, 2019
Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are proteins that are ubiquitously expressed, and are present in the nucleus, cytosol, and mitochondria.
Anna Signorile, Giuseppe Sgaramella, Francesco Bellomo, Domenico De Rasmo   +3 more
doaj   +1 more source

Protein Profile of Multiple Myeloma‐Derived Extracellular Vesicles for the Discovery of Novel Myeloma‐Related Biomarkers

Cancer Science, EarlyView.
Comparison of extracellular vesicles with parental cells through proteomic profiling, followed by an integrated bioinformatic pipeline including disease association and transcriptomic analyses, identifies candidate biomarkers for multiple myeloma. Among these, MIF emerges as a clinically relevant marker, supported by validation in patient samples and ...
Natalia Platonova, Gilda Aiello, Domenica Ronchetti, Valentina Citro, Rosanna Asselta, Lavinia Casati, Domenica Giannandrea, Elisa Taiana, Antonino Neri, Gloria Sini, Elisabetta Calzavara, Mauro Turrini, Alfonsina D'Amato, Raffaella Chiaramonte   +13 more
wiley   +1 more source

Prohibitin 2: A key regulator of cell function

Life Sciences
The PHB2 gene is located on chromosome 12p13 and encodes prohibitin 2, a highly conserved protein of 37 kDa. PHB2 is a dimer with antiparallel coils, possessing a unique negatively charged region crucial for its mitochondrial molecular chaperone functions.
Bingjie, Zhang, Wentao, Li, Jiaying, Cao, Yanhong, Zhou, Xia, Yuan   +4 more
openaire   +2 more sources

Expression of prohibitin in rat seminiferous epithelium

, 1993
Subtractive hybridization was used to isolate cDNAs highly expressed in stages IX-XI of the cycle of the seminiferous epithelium in the rat. One of the cloned cDNAs was sequenced and shown to be homologous to a previously described cDNA encoding rat ...
Griswold, M D, Choongkittaworn, N M, Danner, D B, Kim, K H   +3 more
core   +1 more source