Results 41 to 50 of about 24,430,487 (196)
Prohibitin 1 in liver injury and cancer [PDF]
, 2020 UNLABELLED: Prohibitin 1 is an evolutionary conserved and ubiquitously expressed protein that exerts different biological functions depending on its subcellular localization.
Barbier-Torres, Lucía, Lu, Shelly C
core +1 more source
Renal Failure, 2013 Prohibitin (PHB), a ubiquitous protein, plays a number of different molecular functions, and it is mainly located on the inner mitochondrial membrane and nuclei.
Tian-Biao, Zhou, Yuan-Han, Qin
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Studies on Fortilin-Prohibitin Interaction [PDF]
, 2013 : Apoptosis, programmed cell death, is a tightly regulated process that occurs in development, in tissue maintenance and turnover, and in regulating the immune system.
Doan, Hung 1982-
core +2 more sources
Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells. [PDF]
PLoS ONE, 2012 Increase in mitochondrial biogenesis has been shown to accompany brown and white adipose cell differentiation. Prohibitins (PHBs), comprised of two evolutionarily conserved proteins, prohibitin-1 (PHB1) and prohibitin-2 (PHB2), are present in a high ...
Dong Liu +9 more
doaj +1 more source
Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier [PDF]
The American Journal of Pathology, 2016 Mitochondrial fusion is essential for maintenance of mitochondrial function and requires the prohibitin ring complex subunit prohibitin-2 (PHB2) at the mitochondrial inner membrane. Loss of the stomatin/PHB/flotillin/HflK/C (SPFH) domain containing protein PHB2 causes mitochondrial dysfunction and defective mitochondria-mediated signaling, which is ...
Christina, Ising +16 more
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Parasites & Vectors, 2018 Background Leishmaniasis, a disease caused by parasites of the genus Leishmania, infects roughly 12 million people worldwide, with about two million new cases per year. Prohibitins (PHBs) are highly conserved proteins belonging to the stomatin-prohibitin
Teresa Cruz-Bustos +4 more
doaj +1 more source
Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue [PDF]
JCI Insight, 2016 We have previously identified prohibitin (PHB) and annexin A2 (ANX2) as proteins interacting on the surface of vascular endothelial cells in white adipose tissue (WAT) of humans and mice. Here, we demonstrate that ANX2 and PHB also interact in adipocytes.
Ahmad Salameh +7 more
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Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation [PDF]
Journal of Cell Science, 2004 In a yeast two-hybrid screen using the full-length Akt as bait, we found that prohibitin 2 (PHB2) specifically interacts with Akt. The C terminus of Akt (amino acids 413-480) and a central region of PHB2 (amino acids 120-232) are responsible for their mutual interaction. PHB2 acts as a transcriptional repressor in cells.
Sun, Luguo +3 more
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Virulence, 2022 The vegetative insecticidal proteins (Vip3A) secreted by some Bacillus thuringiensis (Bt) strains during vegetative growth are regarded as a new generation of insecticidal toxins. Like insecticidal crystal proteins, they are also used in transgenic crops
Baoju An +5 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008 Stomatin is a member of a large family of proteins including prohibitins, HflK/C, flotillins, mechanoreceptors and plant defense proteins, that are thought to play a role in protein turnover. Using different proteomic approaches, we and others have identified SLP-2, a member of the stomatin gene family, as a component of the mitochondria. In this study,
Da Cruz, Sandrine +7 more
openaire +3 more sources