Results 81 to 90 of about 24,430,487 (196)
Prohibitin affects the conformation of p53.
, 2013 A) MCF-7 cells were transfected with siRNA against prohibitin for 48 hours. The inhibition of prohibitin expression was confirmed and the levels of p53 determined by immunoblot.
James J. Manfredi (346732) +4 more
core +1 more source
Microbiology SpectrumThe SPFH (stomatin, prohibitin, flotillin, and HflK/HflC) protein superfamily is conserved across all domains of life. Fungal SPFH proteins are required for respiration, stress adaptation, and membrane scaffolding. In the yeast Candida albicans, stomatin-
Hyunjeong Kim +7 more
doaj +1 more source
Microbial CellUbiquitously expressed Prohibitin-1 (PHB1) and Prohibitin-2 (PHB2) serve pleiotropic functions in cellular processes, including signal transduction, mitochondrial metabolism and dynamics, and lipid raft formation. Located in phospholipid-rich subcellular
Grecia O. Rivera-Palomino +1 more
doaj +1 more source
Discovery of PHB1 as a Novel Candidate Gene in Dominant Optic Atrophy
Clinical Genetics, Volume 110, Issue 2, Page 165-171, August 2026.A heterozygous PHB1 missense variant (p.Ser147Phe) segregates with autosomal dominant optic atrophy in a multi‐generation family. Structural and cellular analyses suggest altered mitochondrial dynamics, identifying PHB1 as a novel candidate gene for hereditary optic neuropathy. ABSTRACT Hereditary optic neuropathies comprise a genetically heterogeneous
Marija Volk +13 more
wiley +1 more source
Leishmania cell surface prohibitin: role in host-parasite interaction
, 2010 Proteins selectively upregulated in infective parasitic forms could be critical for disease pathogenesis. A mammalian prohibitin orthologue is upregulated in infective metacyclic promastigotes of Leishmania donovani, a parasite that causes visceral ...
Jain, Rohit +3 more
core +1 more source
Inhibition of insulin/IGF‐1 receptor signaling protects from mitochondria‐mediated kidney failure
EMBO Molecular Medicine, 2015 Mitochondrial dysfunction and alterations in energy metabolism have been implicated in a variety of human diseases. Mitochondrial fusion is essential for maintenance of mitochondrial function and requires the prohibitin ring complex subunit prohibitin‐2 (
Christina Ising +19 more
doaj +1 more source
The Journal of Pathology: Clinical Research, 2022 Papillary thyroid carcinoma tall cell variant (PTC‐TCV), a form of PTC regarded as an aggressive subtype, shares several morphologic features with oncocytic tumors.
Oleksiy Tsybrovskyy +11 more
doaj +1 more source
New Phytologist, Volume 251, Issue 3, Page 1329-1343, August 2026.Overview of the results. Phylogenetic analyses of 36 assembly factors of photosystem II (PSII) and 13 proteins involved in membrane dynamics summarized in Siebenaller & Schneider (2023) were performed to investigate the taxonomic distributions and structural differences between the thylakoid‐less Gloeobacterales and the Phycobacteria. Summary Thylakoid
Louise Hambücken +2 more
wiley +1 more source
SARS‐CoV‐2 and Cancer Biology: Exploring the Mechanistic Links
Cancer Reports, Volume 9, Issue 7, July 2026.ABSTRACT Background Five years after the emergence of SARS‐CoV‐2 and the declaration of the COVID‐19 pandemic, the long‐term implications of COVID‐19 for cancer biology remain incompletely understood. Beyond the major disruptions in cancer screening, diagnosis, and treatment observed worldwide, increasing attention has focused on whether SARS‐CoV‐2 ...
Andrea Orue +2 more
wiley +1 more source
Scientific Reports, 2018 Prohibitin 2(PHB2) is a member of the SFPH trans-membrane family proteins. It is a highly conserved and functionally diverse protein that plays an important role in preserving the structure and function of the mitochondria.
Ying Shi +5 more
doaj +1 more source