Results 41 to 50 of about 47,460 (254)

A Nuclear Gene Encoding Mitochondrial Proline Dehydrogenase, an Enzyme Involved in Proline Metabolism, Is Upregulated by Proline but Downregulated by Dehydration in Arabidopsis [PDF]

The Plant Cell, 1996
Proline is one of the most common compatible osmolytes in water-stressed plants. The accumulation of proline in dehydrated plants is caused both by the activation of proline biosynthesis and by the inactivation of proline degradation; a decrease in the level of accumulated proline in rehydrated plants is caused both by the inhibition of proline ...
T, Kiyosue, Y, Yoshiba, K, Yamaguchi-Shinozaki, K, Shinozaki   +3 more
openaire   +2 more sources

Evidence for Hysteretic Substrate Channeling in the Proline Dehydrogenase and Δ1-Pyrroline-5-carboxylate Dehydrogenase Coupled Reaction of Proline Utilization A (PutA) [PDF]

Journal of Biological Chemistry, 2014
PutA (proline utilization A) is a large bifunctional flavoenzyme with proline dehydrogenase (PRODH) and Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH) domains that catalyze the oxidation of l-proline to l-glutamate in two successive reactions. In the PRODH active site, proline undergoes a two-electron oxidation to Δ(1)-pyrroline-5-carboxlylate, and
Moxley, Michael A, Sanyal, Nikhilesh, Krishnan, Navasona, Tanner, John J., Becker, Donald F.   +4 more
openaire   +2 more sources

L-Proline Activates Mammalian Target of Rapamycin Complex 1 and Modulates Redox Environment in Porcine Trophectoderm Cells

Biomolecules, 2021
L-proline (proline) is a key regulator of embryogenesis, placental development, and fetal growth. However, the underlying mechanisms that support the beneficial effects of proline are largely unknown.
Ning Liu, Ying Yang, Xuemeng Si, Hai Jia, Yunchang Zhang, Da Jiang, Zhaolai Dai, Zhenlong Wu   +7 more
doaj   +1 more source

Toxicity of Free Proline Revealed in an Arabidopsis T-DNA-Tagged Mutant Deficient in Proline Dehydrogenase [PDF]

Plant and Cell Physiology, 2003
The toxicity of proline (Pro) to plant growth has raised questions despite its protective functions in response to environmental stresses. To evaluate Pro toxicity, we isolated an Arabidopsis T-DNA-tagged mutant, pdh, that had a defect in Pro dehydrogenase (AtProDH), which catalyzes the first step of Pro catabolism.
Tokihiko, Nanjo, Miki, Fujita, Motoaki, Seki, Tomohiko, Kato, Satoshi, Tabata, Kazuo, Shinozaki   +5 more
openaire   +2 more sources

Pyrroline-5-carboxylate Dehydrogenase Is an Essential Enzyme for Proline Dehydrogenase Function during Dark-induced Senescence in \emphArabidopsis\emph Thaliana

, 2023
International audienceDuring leaf senescence, nitrogen is remobilized and carbon backbones are replenished by amino acid catabolism, with many of the key reactions occurring in mitochondria.
Guivarc'H, Anne, Planchais, Séverine, Bordenave-Jacquemin, Marianne, Yao Zheng, Clément, Gilles, Cabassa-Hourton, Cécile, Nina Durand, Marianne Bordenave‐Jacquemin, Lebreton, Sandrine, Crilat, Emilie, Durand, Nina, Carol, Pierre, Sandrine Lebreton, Zheng, Yao, Savouré, Arnould, Emilie Crilat, Matthieu Dacher, Anne Guivarc'h, Arnould Savouré, Gilles Clément, Dacher, Matthieu, Pierre Carol, Cécile Cabassa‐Hourton, Séverine Planchais, Corentin Dourmap, Dourmap, Corentin   +25 more
core   +1 more source

Hydrogen Sulfide Treatment Alleviates Chilling Injury in Cucumber Fruit by Regulating Antioxidant Capacity, Energy Metabolism and Proline Metabolism

Foods, 2022
Although low-temperature storage could maintain the quality of fruits and vegetables, it may also result in chilling injury (CI) in cold-sensitive produce, such as cucumbers.
Jingda Wang, Yaqin Zhao, Zhiqian Ma, Yonghua Zheng, Peng Jin   +4 more
doaj   +1 more source

Proline metabolism.

, 2013
Abbreviations: PRO, proline; PRODH, proline oxidase (a.k.a. proline dehydrogenase); P5CR, pyrroline-5-carboxylate reductase; P5C, pyrroline-5-carboxylate; GSA, glutamic semialdehyde; P5CDH, pyrroline-5-carboxylate dehydrogenase; P5CS, pyrroline-5 ...
Brian Suárez Mantilla (435600), Maria Carolina Elias (243026), Lisvane Silva Paes (267021), Patrícia Diogo de Melo (435603), Erich B. Tahara (284264), Ariel Mariano Silber (167356), Elisabeth Mieko Furusho Pral (435602), Alicia J. Kowaltowski (284269), Flávia Menezes Zimbres (435601)   +8 more
core   +1 more source

A bienzyme electrochemical biosensor for the detection of collagen l-hydroxyproline

Sensing and Bio-Sensing Research, 2015
l-hydroxyproline (l-Hyp: trans-4-hydroxy-l-proline) is commonly found at high concentrations in connective tissue proteins such as collagen. It is a remarkably useful molecular marker because variation in the level of l-Hyp is associated with various ...
Hiroaki Sakamoto, Kazuya Watanabe, Ayako Koto, Gaku Koizumi, Takenori Satomura, Seiya Watanabe, Shin-ichiro Suye   +6 more
doaj   +1 more source

Variability of leaf pubescence characteristics in transgenic tobacco lines with partial proline dehydrogenase gene suppression

Biologia Plantarum, 2022
Proline, an amino acid, plays an important role in plants, and it is involved in stress resistance and development. Earlier, to study the proline role in maintaining stress resistance in plants, we obtained genetically modified transgenic lines of ...
S.M. IBRAGIMOVA, M.A. GENAEV, A.V. KOCHETOV, D.A. AFONNIKOV   +3 more
doaj   +1 more source

Involvement of the β3-α3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A [PDF]

Biochemistry, 2013
Proline utilization A (PutA) from Escherichia coli is a membrane-associated trifunctional flavoenzyme that catalyzes the oxidation of proline to glutamate and moonlights as a transcriptional regulator. As a regulatory protein, PutA represses transcription of the put regulon, which contains the genes encoding PutA and the proline transporter PutP.
Zhu, Weidong, Haile, Ashley M, Singh, Ranjan K, Larson, John D, Smithen, Danielle, Chan, Jie Y, Tanner, John J, Becker, Donald F   +7 more
openaire   +2 more sources