Proline is emerging as a critical component of drought tolerance and fine tuning of its metabolism under stress affects the plants sensitivity and response to stress.
D. Kaur, S. K. Grewal, J. Kaur, S. Singh
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The study examines the effect of acclimation on the antioxidant system and proline metabolism in cucumber leaves subjected to 100 and 150 NaCl stress.
Marcin Naliwajski, Maria Skłodowska
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Structure of the proline dehydrogenase domain of the multifunctional PutA flavoprotein [PDF]
The PutA flavoprotein from Escherichia coli plays multiple roles in proline catabolism by functioning as a membrane-associated bi-functional enzyme and a transcriptional repressor of proline utilization genes. The human homolog of the PutA proline dehydrogenase (PRODH) domain is critical in p53-mediated apoptosis and schizophrenia.
Yong-Hwan, Lee +4 more
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The sodium/proline transporter PutP of Helicobacter pylori. [PDF]
Helicobacter pylori is cause of chronic gastritis, duodenal ulcer and gastric carcinoma in humans. L-proline is a preferred energy source of the microaerophilic bacterium. Previous analyses revealed that HpputP and HpputA, the genes that are predicted to
Araceli Rivera-Ordaz +8 more
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Proline/P5C cycle between mitochondria and cytosol, play important roles in energy supply and ROS (Reactive oxygen species) generation in mammalian cell.
Wenhan Ying +6 more
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Proline metabolism-related gene expression in four potato genotypes in response to drought stress
Drought severely limits potato yield. The aim of this work was to study a response of plantlets of four potato genotypes to polyethylene glycol (PEG 6000)-induced drought stress in both physiological and molecular levels. The drought-tolerant and drought-
Y. LIU, L. WANG, Y. LI, X. LI, J. ZHANG
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A Nuclear Gene Encoding Mitochondrial Proline Dehydrogenase, an Enzyme Involved in Proline Metabolism, Is Upregulated by Proline but Downregulated by Dehydration in Arabidopsis [PDF]
Proline is one of the most common compatible osmolytes in water-stressed plants. The accumulation of proline in dehydrated plants is caused both by the activation of proline biosynthesis and by the inactivation of proline degradation; a decrease in the level of accumulated proline in rehydrated plants is caused both by the inhibition of proline ...
T, Kiyosue +3 more
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The regulatory mechanisms of proline and hydroxyproline metabolism: Recent advances in perspective
For diverse human tumors, growth and metastasis are dependent on proline synthesis, but the mechanisms underlying this association are not clear. Proline incorporated into collagen is primarily synthesized from glutamine.
James M. Phang
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The effect of folic acid treatment on the post-harvest life of cucumber through influencing the activity of enzymes involved in the biosynthesis of proline, polyamine, and chlorophyll-degradation [PDF]
In this study, the mechanism of cold stress tolerance in cucumber fruits pretreated with folic acid was investigated. Control group and the group treated with 5 mgL-1 folic acid were stored for 15 days at 4 °-C.
Parviz Malekzadeh
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Evidence for Hysteretic Substrate Channeling in the Proline Dehydrogenase and Δ1-Pyrroline-5-carboxylate Dehydrogenase Coupled Reaction of Proline Utilization A (PutA) [PDF]
PutA (proline utilization A) is a large bifunctional flavoenzyme with proline dehydrogenase (PRODH) and Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH) domains that catalyze the oxidation of l-proline to l-glutamate in two successive reactions. In the PRODH active site, proline undergoes a two-electron oxidation to Δ(1)-pyrroline-5-carboxlylate, and
Moxley, Michael A +4 more
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