Results 51 to 60 of about 46,423 (228)

Proline dehydrogenase: a key enzyme in controlling cellular homeostasis

Frontiers in Bioscience, 2012
Proline dehydrogenase (ProDH), also called proline oxidase (POX), is a universal enzyme in living organisms. It catalyzes the oxidation of L-proline to delta1-pyrroline-5-carboxylate leading to the release of electrons, which can be transferred to either electron transfer systems or to molecular oxygen.
Caroline, Servet, Thanos, Ghelis, Luc, Richard, Aviah, Zilberstein, Arnould, Savoure   +4 more
openaire   +2 more sources

Характеристика трансгенних рослин соняшника (Helianthus annuus L.) з дволанцюговим РНК супрессором гена проліндегідрогенази

Фактори експериментальної еволюції організмів, 2016
Aim. The obtaining of osmotolerant form of sunflower (Helianthus annuus L.) by siRNA-technology. Methods. Agrobacterium-mediated transformation using LBA4404 harboring pBi2E with double-stranded RNA-suppressor, produced based on the ProDH1 gene of ...
А. Г. Комісаренко, С. І. Михальська, В. М. Курчій, О. М. Тищенко   +3 more
doaj  

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

Advanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee, Jumi Kim, Taehan Yoon, So Hyun Kwon, Su Chan Park, Dohyun Chun, Dohyeong Kim, Eun Jung Park, Hyunwoo Kim, Ji Min Lee   +9 more
wiley   +1 more source

Perturbation of folding and reassociation of lactate dehydrogenase by proline and trimethylamine oxide [PDF]

European Journal of Biochemistry, 2003
Investigations of protein–solute interactions typically show that osmolytes favor native conformations. In this study, the effects of representative compatible and counteracting osmolytes on the reactivation of lactate dehydrogenase from two different conformational states were explored.
Oscar P, Chilson, Anne E, Chilson
openaire   +2 more sources

Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade

Cell Reports, 2016
Proline dehydrogenase (PRODH), which degrades L-proline, resides within the schizophrenia-linked 22q11.2 deletion suggesting a role in disease. Supporting this, elevated L-proline levels have been shown to increase risk for psychotic disorders.
Gregg W. Crabtree, Alan J. Park, Joshua A. Gordon, Joseph A. Gogos   +3 more
doaj   +1 more source

OsProDH Negatively Regulates Thermotolerance in Rice by Modulating Proline Metabolism and Reactive Oxygen Species Scavenging

Rice, 2020
Background Global warming threatens rice growth and reduces yields. Proline plays important roles in plant abiotic stress tolerance. Previous research demonstrated that engineering proline metabolism-related genes can enhance tolerance to freezing and ...
Mingxin Guo, Xiaotian Zhang, Jiajia Liu, Linlin Hou, Hanxiao Liu, Xusheng Zhao   +5 more
doaj   +1 more source

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

Nicotinamide Adenine Dinucleotide-dependent Proline Dehydrogenase in Chlorella [PDF]

Plant Physiology, 1974
An NAD-linked dehydrogenase from Chlorella pyrenoidosa Chick catalyzing the conversion of l-proline to Delta(1)-pyrroline-5-carboxylic acid was partially purified. Delta(1)-Pyrroline-5-carboxylic acid was identified as the product by co-chromatography of it and its o-aminobenzaldehyde derivative with authentic compounds. The enzyme is NAD and l-proline
A D, McNamer, C R, Stewart
openaire   +2 more sources

The effect of magnetized water on the growth and some biochemical parameters of squash (Cucurbita pepo) plants under toxicity of herbicide trifluralin

یافته‌های نوین در علوم زیستی, 2020
To investigate the effect of herbicide Trifluralin and the role of magnetized water on enzymatic activities and content of proline and growth substances including gibberellin (GA3) and cytokinin (6- benzyl amino purine), an experiment was conducted using
Nasrin Esmailnejad, Jalil Khara, Mehrdad Akhgari   +2 more
doaj  

The effect of water deficit and excess copper on proline metabolism in Nicotiana benthamiana

Biologia Plantarum, 2012
Fluctuation in proline content is a widespread phenomenon among plants in response to heavy metal stress. To distinguish between the participation of water deficit and copper on changes in proline metabolism, potted plants and floating leaf discs of ...
H. -M. Ku, C. -W. Tan, Y. -S. Su, C. -Y. Chiu, C. -T. Chen, F. -J. Jan   +5 more
doaj   +1 more source