Results 91 to 100 of about 2,628 (173)
Investigation of genetic association between PRODH gene and schizophrenia in Iranian population [PDF]
, 2012 Schizophrenia is a complicated, debilitative mental disorder. Evidence is emerging for the association of polymorphisms in PRODH gene and increased risk of schizophrenia.
Heidari keshel, Saeed +3 more
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Brain and Behavior, Volume 15, Issue 5, May 2025.The study focused on a mouse model of depression induced by lipopolysaccharides (LPS) and employed innovative multi‐omics approaches, including two‐dimensional gel electrophoresis (2‐DE) for proteomics, liquid chromatography–mass spectrometry (LC–MS) for metabolomics, and real‐time polymerase chain reaction (PCR) microarray technology to analyze the ...
Wen‐Wen Li +10 more
wiley +1 more source
Evidence for gliadin antibodies as causative agents in schizophrenia. [PDF]
, 2010 Antibodies to gliadin, a component of gluten, have frequently been reported in schizophrenia. Highly immunogenic B cell epitopes along its length are homologous to numerous proteins relevant to schizophrenia, including members of the DISC1 interactome ...
Chris J. Carter
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Health Science Reports, Volume 8, Issue 3, March 2025.ABSTRACT Background and Aims Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a poorly understood etiology. Recent studies have suggested that metabolic dysregulation might be linked to the development of ASD; however, causal relationships remain unclear.
Wenhua Li, Suya Ma, Yunong Tian
wiley +1 more source
Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats [PDF]
, 2016 BACKGROUND: There is a spectacular rise in the global prevalence of type 2 diabetes mellitus (T2DM) due to the worldwide obesity epidemic. However, a significant proportion of T2DM patients are non-obese and they also have an increased risk of ...
Csonka, Csaba +12 more
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Journal of Cellular Physiology, Volume 240, Issue 1, January 2025.Abstract Legumain is a cysteine protease broadly associated with inflammation. It has been reported to cleave and activate protease‐activated receptor 2 to provoke pain associated with oral cancer. Outside of gastric and colon cancer, little has been reported on the roles of legumain within the gastrointestinal tract.
Alexander R. Ziegler +8 more
wiley +1 more source
Proline metabolism and transport in plant development [PDF]
, 2018 Proline fulfils diverse functions in plants. As amino acid it is a structural component of proteins, but it also plays a role as compatible solute under environmental stress conditions.
Funck, Dietmar +3 more
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Association of 757 C/T polymorphismin PRODH gene with Schizophrenia in Iranian population [PDF]
, 2013 Evidence is emerging for the association of polymorphisms in PRODH gene and increased risk of schizophrenia. In this project, peripheral blood sampling was obtained from 175 schizophrenia patients that their diseases were confirmed by psychiatrists.
Fakour, Yousef +5 more
core +2 more sources
Proline Tagging for Stress Tolerance in Plants
International Journal of Genomics, Volume 2025, Issue 1, 2025.In environments with high levels of stress conditions, plants accumulate various metabolic products under stress conditions. Among these products, amino acids have a cardinal role in supporting and maintaining plant developmental processes. The increase in proline content and stress tolerance in plants has been found optimistic, suggesting the ...
Naveed Ul Mushtaq +7 more
wiley +1 more source
Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities [PDF]
, 2018 Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the last step in proline synthesis. Deficiency of PYCR1, caused by a defect in PYCR1, was recently described in patients with cutis laxa, intrauterine growth retardation, developmental dysplasia of ...
Baumer, Alessandra +9 more
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