Results 111 to 120 of about 2,628 (173)

Exogenous γ-aminobutyric acid promotes 2-acetyl-1-pyrroline biosynthesis by enriching glutamate and optimizing its metabolic flux in pumpkin

open access: yesFrontiers in Plant Science
Aroma is a key quality trait determining the flavor and market competitiveness of pumpkins. Its characteristic fragrance mainly comes from 2-acetyl-1-pyrroline (2-AP), whose biosynthesis shares the common precursor with γ-aminobutyric acid (GABA ...
Jingjing Chang   +6 more
doaj   +1 more source

First Evidence for Substrate Channeling between Proline Catabolic Enzymes \u3ci\u3eA VALIDATION OF DOMAIN FUSION ANALYSIS FOR PREDICTING PROTEIN-PROTEIN INTERACTIONS\u3c/i\u3e [PDF]

open access: yes, 2015
Background: PRODH and P5CDH from Thermus thermophilus are monofunctional enzymes in proline catabolism. Results: Steady-state kinetics and intermediate trapping data show the PRODH and P5CDH reactions are coupled by a channeling step.
Arentson, Benjamin W   +3 more
core   +1 more source

The circUbqln1, regulated by XBP1s, interplays with 14–3–3ζ to inhibit collagen synthesis and promote osteoarthritis by controlling PRODH activity and proline metabolism

open access: yesJournal of Advanced Research
Introduction: Osteoarthritis (OA) is a degenerative bone disease associated with ageing, characterized by joint pain, stiffness, swelling and deformation. Currently, pharmaceutical options for the clinical treatment of OA are very limited.
Naibo Feng   +17 more
doaj   +1 more source

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