Results 101 to 110 of about 1,773 (164)

Unravelling the role of proline dehydrogenase (PRODH) in lung adenocarcinoma: implications for cellular senescence and the tumor microenvironment

Proline dehydrogenase (PRODH) is a mitochondrial flavoenzyme that catalyzes proline oxidation. The electrons generated from this reaction can be used to produce ATP or ROS, potentially affecting several cellular processes, such as survival, apoptosis ...
Raffaella Cinquetti, Paola Campomenosi, Antonino Bruno, Elena Berno, Priscilla Chiofalo, Maria Teresa Palano   +5 more
core  

PROLINE DEHYDROGENASE EXPRESSION, REGULATION AND FUNCTION IN NON-SMALL CELL LUNG CARCINOMA

, 2019
Non-Small Cell Lung Cancer (NSCLC) is one of the most frequent and deadliest cancers and comprises two main histotypes, adenocarcinoma (ADC) and squamocellular carcinoma (SCC).
Fausto Sessa, Paola Campomenosi, Anna Maria Chiaravalli, Sarah Grossi   +3 more
core  

Proline dehydrogenase (oxidase) 1 (PRODH; POX); SNP rs450046; SNP rs4819756; SNP rs2870983 [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

A dual role of Proline Dehydrogenase in Lung Cancer

Lung cancer is still a global health problem. Present therapeutic approaches, among which Tyrosine Kinase Inhibitors (TKIs), have improved outcomes of patients with lung adenocarcinoma (LUAD). However, resistance mechanisms occur.
Raffaella Cinquetti, Giorgia Foggetti, Virginia Guzzeloni, Paola Campomenosi, Laura Pulze, Priscilla Chiofalo, Elena Berno, Samuele Valci   +7 more
core  

"Alternative" or integrated role of mitochondrial glycerol-3-phosphate dehydrogenase. [PDF]

Proc Natl Acad Sci U S A
Lemieux H, Joël Lucien Chevret C, Gnaiger E.   +2 more
europepmc   +1 more source

Evidence for Proline Catabolic Enzymes in the Metabolism of Thiazolidine Carboxylates

Thiazolidine carboxylates such as thiazolidine-4-carboxylate (T4C) and thiazolidine-2-carboxylate (T2C) are naturally occurring sulfur analogues of proline. These compounds have been observed to have both beneficial and toxic effects in cells. Given that
John J. Tanner (1333191), Yizi Mao (11669872), Thomas G. Smith (9040705), Javier Seravalli (1264638), Donald F. Becker (742832), Martha Morton (566328)   +5 more
core   +1 more source

Structural Principles of Covalent Flavin Modification in Oxidoreductases. [PDF]

Biochemistry
Tanner JJ.
europepmc   +1 more source

Dysregulated Proline Metabolism Exacerbates Hepatocellular Carcinoma Metastasis via EPRS1-Mediated mRNA Translation. [PDF]

Cancer Commun (Lond)
Zhang H, Gu L, Su X, Chen W, Tan M, Yu H, Zhou H, Gao T, Wang Z, Chen X, Chen W, Chen J, Cheng S.   +12 more
europepmc   +1 more source

Measurement of δ¹-Pyrroline-5-Carboxylic Acid in Plant Extracts for Physiological and Biochemical Studies. [PDF]

Metabolites
Forlani G, Trupia F.
europepmc   +1 more source

Consumption of L-Proline as Energy Substrate by Cultured Primary Rat Astrocytes. [PDF]

Neurochem Res
Spellerberg P, Dringen R.
europepmc   +1 more source