Results 81 to 90 of about 204,753 (161)

Study of regulatory factors in Non Small Cell Lung Cancer: a role for Proline Dehydrogenase? [PDF]

, 2021
Proline dehydrogenase (PRODH) is a mitochondrial inner-membrane and stressinducible flavoenzyme catalysing the first step in the proline degradation pathway. Due to its distinctive chemical structure, in fact, proline is metabolized by a distinct set
GROSSI SARAH
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Biochemical, structural, and cellular characterization of S-but-3-yn-2-ylglycine as a mechanism-based covalent inactivator of the flavoenzyme proline dehydrogenase. [PDF]

Arch Biochem Biophys
The mitochondrial flavoenzymes proline dehydrogenase (PRODH) and hydroxyproline dehydrogenase (PRODH2) catalyze the first steps of proline and hydroxyproline catabolism, respectively.
Meeks KR, Ji J, Scott GK, Campbell AC, Nix JC, Tadeo A, Ellerby LM, Benz CC, Tanner JJ.   +8 more
europepmc   +2 more sources

High yields of active Thermus thermophilus proline dehydrogenase are obtained using maltose-binding protein as a solubility tag.

, 2015
Proline dehydrogenase (ProDH) catalyzes the FAD-dependent oxidation of proline to ¿1-pyrroline-5-carboxylate, the first step of proline catabolism in many organisms.
Huijbers, M.M.E., van Berkel, W.J.H., Berkel, W.J.H., van   +2 more
core   +1 more source

Morpho-biochemical plasticity and efficient crosstalk in proline metabolism governs stress resilience in indica rice

Environmental and Experimental Botany
Plants face recurrent challenges from various abiotic stresses, including salt and drought. Being sessile, they employ adaptive strategies through root architectural modifications, enhanced antioxidant activity, accumulation of osmoprotectants like ...
Shivani Shivani, Soumyayan Roy, Arpita Das, Joydeep Banerjee   +3 more
doaj   +1 more source

Melatonin Combined with 1-Methylcyclopropene Regulates Proline Metabolism to Alleviate Chilling Injury in Postharvest Hami Melons [PDF]

Shipin Kexue
To investigate the effects of melatonin (MT) in combination with 1-methylcyclopropene (1-MCP) on postharvest proline metabolism and chilling injury in Hami melons, this study included four treatments: control (distilled water immersion + distilled water ...
WANG Xiaobing, JIA Meihui, GAO Zhongchuan, CHEN Haixin, CHEN Xiaojie, ZHANG Zonghao, WENG Wanlin, WANG Yu, WANG Jing
doaj   +1 more source

Molecular and Biochemical Characterization of the proline dehydrogenase of T. cruzi, a possible therapeutical target .

, 2010
Os nossos resultados demonstraram a atividade enzimática prolina desidrogenase (PRODH) do produto do gene anotado como codificante de uma prolina oxidase na base dados do genoma de Trypanosoma cruzi.
Lisvane Paes Vieira, Vieira, Lisvane Paes   +1 more
core   +1 more source

Exogenous proline enhances salt acclimation in soybean seedlings: Modifying physicochemical properties and controlling proline metabolism through the ornithine-glutamate dual pathway

Ecotoxicology and Environmental Safety
Soil salinization has emerged as a major factor negatively affecting soil quality and plant productivity. Proline, functioning as an osmotic regulator, has been proposed as an effective strategy for enhancing plant tolerance to salt stress.
Lei Yan, Mu Lu, Muhammad Riaz, Kaiqing Tong, Hualong Yu, Guang Gao, Yusheng Niu   +6 more
doaj   +1 more source

Differentiation-Dependent Regulation of Human Endogenous Retrovirus K Sequences and Neighboring Genes in Germ Cell Tumor Cells

Frontiers in Microbiology, 2018
Under physiological conditions, most human endogenous retroviruses (HERVs) are transcriptionally silent. However, re-activation of HERVs is observed under pathological conditions like inflammation or cancer.
Thomas Mueller, Claudia Hantsch, Ines Volkmer, Martin S. Staege   +3 more
doaj   +1 more source

l-Proline Alleviates Kidney Injury Caused by AFB1 and AFM1 through Regulating Excessive Apoptosis of Kidney Cells

Toxins, 2019
The toxicity and related mechanisms of aflatoxin B1 (AFB1) and aflatoxin M1 (AFM1) in the mouse kidney were studied, and the role of l-proline in alleviating kidney damage was investigated.
Huiying Li, Songli Li, Huaigu Yang, Yizhen Wang, Jiaqi Wang, Nan Zheng   +5 more
doaj   +1 more source

Proline dehydrogenase activity of mungbean rhizobia and their proline prototrophs in relation to their efficacy in symbiotic association

, 1999
1234-1240Proline dehydrogeanase (ProDH) is a key enzyme which catabolises proline to yield additional energy to support N2 fixation in legume root nodules. Tn5 mutagenesis of four mungbean infeccting Rhizobium  strains Mo-2 ,Mo-6 PP9038 (PH9022) and G-
Khurana, A L, Dudeja, S S, Sharma, H R, Malik, M S, Chaudhary, S   +4 more
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