Results 21 to 30 of about 1,778 (165)

Catechol‐o‐methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression [PDF]

Synapse, 2003
AbstractCatechol‐o‐methyltransferase (COMT) and proline dehydrogenase (PRODH) may both be susceptibility genes for schizophrenia. As part of the evaluation of their roles in psychosis, we used reverse transcription–polymerase chain reaction to measure COMT and PRODH mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, major ...
Tunbridge, E, Burnet, P, Sodhi, MS, Harrison, P   +3 more
openaire   +3 more sources

Electrochemical behavior of dye-linked L-proline dehydrogenase on glassy carbon electrodes modified by multi-walled carbon nanotubes [PDF]

Beilstein Journal of Nanotechnology, 2010
A glassy carbon electrode (GC) was modified by multi-walled carbon nanotubes (MWCNTs). The modified electrode showed a pair of redox peaks that resulted from the oxygen-containing functional groups on the nanotube surface.
Haitao Zheng, Leyi Lin, Yosuke Okezaki, Ryushi Kawakami, Haruhiko Sakuraba, Toshihisa Ohshima, Keiichi Takagi, Shin-ichiro Suye   +7 more
doaj   +2 more sources

SlgA, encoded by the homolog of the human schizophrenia-associated gene PRODH, acts in clock neurons to regulate Drosophila aggression [PDF]

Disease Models & Mechanisms, 2017
Mutations in the proline dehydrogenase gene PRODH are linked to behavioral alterations in schizophrenia and as part of DiGeorge and velo-cardio-facial syndromes, but the role of PRODH in their etiology remains unclear.
Liesbeth Zwarts, Veerle Vulsteke, Edgar Buhl, James J. L. Hodge, Patrick Callaerts   +4 more
doaj   +3 more sources

Proline–Nitrogen Metabolic Coordination Mediates Cold Priming-Induced Freezing Tolerance in Maize [PDF]

Plants
Cold stress critically restricts maize seedling growth in Northeast China, yet the mechanism by which cold priming (CP) enhances cold tolerance through proline–nitrogen metabolic networks remains unclear.
Zhijia Gai, Lei Liu, Na Zhang, Jingqi Liu, Lijun Cai, Xu Yang, Ao Zhang, Pengfei Zhang, Junjie Ding, Yifei Zhang   +9 more
doaj   +2 more sources

Sources of superoxide/H2O2 during mitochondrial proline oxidation

Redox Biology, 2014
p53 Inducible gene 6 (PIG6) encodes mitochondrial proline dehydrogenase (PRODH) and is up-regulated several fold upon p53 activation. Proline dehydrogenase is proposed to generate radicals that contribute to cancer cell apoptosis.
Christopher Benz, Casey Quinlan, Martin D Brand   +2 more
exaly   +3 more sources

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27) [PDF]

Frontiers in Pharmacology, 2018
Propolis evokes several therapeutic properties, including anticancer activity. These activities are attributed to the action of polyphenols. Previously it has been demonstrated, that one of the most abundant polyphenolic compounds in ethanolic extracts ...
Katarzyna Celińska-Janowicz, Ilona Zaręba, Urszula Lazarek, Joanna Teul, Michał Tomczyk, Jerzy Pałka, Wojciech Miltyk   +6 more
doaj   +2 more sources

Functional Impact of the N-terminal Arm of Proline Dehydrogenase from Thermus thermophilus [PDF]

Molecules, 2018
Proline dehydrogenase (ProDH) is a ubiquitous flavoenzyme that catalyzes the oxidation of proline to Δ1-pyrroline-5-carboxylate. Thermus thermophilus ProDH (TtProDH) contains in addition to its flavin-binding domain an N-terminal arm, consisting of ...
Mieke M. E. Huijbers, Ilona van Alen, Jenny W. Wu, Arjan Barendregt, Albert J. R. Heck, Willem J. H. van Berkel   +5 more
doaj   +2 more sources

Aromatic Rice May Be a New Driving Force for Green and Efficient Food Production in Rice‐Crayfish System

Food and Energy Security
Rice‐crayfish system (RCS) is an integrated farming technology that benefits grain production, food safety, and green sustainable agricultural development.
Bin Du, Jinfu Hu, Ziran Tang, Xueer Lin, Caise Ya, Wujun Zhang, Yongqun Tang, Lihe Zhang, Xiong Yao   +8 more
doaj   +2 more sources

Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis [PDF]

BMC Plant Biology, 2010
Background Proline (Pro) accumulation is a widespread response of prokaryotic and eukaryotic cells subjected to osmotic stress or dehydration. When the cells are released from stress, Pro is degraded to glutamate by Pro-dehydrogenase (ProDH) and ...
Müller Gudrun, Eckard Sonja, Funck Dietmar   +2 more
doaj   +3 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism. [PDF]

Adv Sci (Weinh)
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Ying H, Fan H, Wang Y, Jiang R, Cai D, Cheng H, Wang H, Jiang C, Liang P.   +8 more
europepmc   +2 more sources