Proline–Nitrogen Metabolic Coordination Mediates Cold Priming-Induced Freezing Tolerance in Maize [PDF]
PlantsCold stress critically restricts maize seedling growth in Northeast China, yet the mechanism by which cold priming (CP) enhances cold tolerance through proline–nitrogen metabolic networks remains unclear.
Zhijia Gai +9 more
doaj +2 more sources
Animals, 2020 Proline was reported to improve sperm quality in rams, stallions, cynomolgus monkeys, donkeys, and canines during cryopreservation. However, the underlying mechanism remains unclear.
Zhendong Zhu, Ling Chen, Wenxian Zeng
exaly +3 more sources
Functional Impact of the N-terminal Arm of Proline Dehydrogenase from Thermus thermophilus [PDF]
Molecules, 2018 Proline dehydrogenase (ProDH) is a ubiquitous flavoenzyme that catalyzes the oxidation of proline to Δ1-pyrroline-5-carboxylate. Thermus thermophilus ProDH (TtProDH) contains in addition to its flavin-binding domain an N-terminal arm, consisting of ...
Mieke M. E. Huijbers +5 more
doaj +2 more sources
Food and Energy SecurityRice‐crayfish system (RCS) is an integrated farming technology that benefits grain production, food safety, and green sustainable agricultural development.
Bin Du +8 more
doaj +2 more sources
Characterisation of proline dehydrogenase and its contribution to energy metabolism in Trypanosoma brucei [PDF]
, 2004 Both Leishmania major and Trypanosoma brucei undergo a complicated developmental cycle involving insect vectors and a mammalian host, subjecting these parasites to dramatic changes in their environment.
Lamour, Nadia
core +7 more sources
Targeting Mitochondrial Proline Dehydrogenase (PRODH) with a Suicide Inhibitor as a Novel Anticancer Strategy [PDF]
, 2019 Proline dehydrogenase (PRODH) is a p53-inducible inner mitochondrial membrane protein linked to electron transport and capable of generating mitochondrial glutamate and intracellular ATP, especially under cellular stress conditions.
Becker, Beatrice
openaire +3 more sources
Δ(1)-pyrroline-5-carboxylate/glutamate biogenesis is required for fungal virulence and sporulation. [PDF]
PLoS ONE, 2013 Proline dehydrogenase (Prodh) and Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5Cdh) are two key enzymes in the cellular biogenesis of glutamate.
Ziting Yao +6 more
doaj +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism. [PDF]
Adv Sci (Weinh)The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Ying H +8 more
europepmc +2 more sources
ACTCAT, a Novel cis-Acting Element for Proline- and Hypoosmolarity-Responsive Expression of theProDHGene Encoding Proline Dehydrogenase in Arabidopsis [PDF]
Plant Physiology, 2002 AbstractProline (Pro) is one of the most widely distributed osmolytes in water-stressed plants. We previously isolated from Arabidopsis a gene encoding Pro dehydrogenase (ProDH), a mitochondrial enzyme involved in the first step of the conversion of Pro to glutamic acid. The ProDH gene in Arabidopsis is up-regulated by rehydration after dehydration but
Rie, Satoh +4 more
openaire +2 more sources
Proline Dehydrogenase Contributes to Pathogen Defense in Arabidopsis [PDF]
, 2011 l-Proline (Pro) catabolism is activated in plants recovering from abiotic stresses associated with water deprivation. In this catabolic pathway, Pro is converted to glutamate by two reactions catalyzed by proline dehydrogenase (ProDH) and Ɗ1-pyrroline-5 ...
Nicolás Miguel Cecchini +2 more
core +2 more sources