Results 31 to 40 of about 1,610 (139)

Beneficial Effect of Proline Supplementation on Goat Spermatozoa Quality during Cryopreservation

Animals, 2022
Sperm cryopreservation contributes to the extensive utilization of artificial insemination (AI) in the daily livestock industry. However, due to the presence of few sperm with good biological function in post-thaw goat sperm, its use has been limited for
Weijing Zhang, Lingjiang Min, Yajing Li, Yaning Lang, S. A. Masudul Hoque, Adedeji Olufemi Adetunji, Zhendong Zhu   +6 more
doaj   +1 more source

Mycorrhizal-mediated lower proline accumulation in Poncirus trifoliata under water deficit derives from the integration of inhibition of proline synthesis with increase of proline degradation. [PDF]

PLoS ONE, 2013
Proline accumulation was often correlated with drought tolerance of plants infected by arbuscular mycorrhizal fungi (AMF), whereas lower proline in some AM plants including citrus was also found under drought stress and the relevant mechanisms have not ...
Ying-Ning Zou, Qiang-Sheng Wu, Yong-Ming Huang, Qiu-Dan Ni, Xin-Hua He   +4 more
doaj   +1 more source

Conditions Conducive to the Glutathionylation of Complex I Subunit NDUFS1 Augment ROS Production following the Oxidation of Ubiquinone Linked Substrates, Glycerol-3-Phosphate and Proline

Antioxidants, 2022
Mitochondrial complex I can produce large quantities of reactive oxygen species (ROS) by reverse electron transfer (RET) from the ubiquinone (UQ) pool.
Kevin Wang, Jonathan Hirschenson, Amanda Moore, Ryan J. Mailloux   +3 more
doaj   +1 more source

Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline

Molecules, 2017
Proline utilization A (PutA) is a bifunctional flavoenzyme that catalyzes the two-step oxidation of l-proline to l-glutamate using spatially separated proline dehydrogenase (PRODH) and l-glutamate-γ-semialdehyde dehydrogenase (GSALDH) active sites ...
David A. Korasick, Travis A. Pemberton, Benjamin W. Arentson, Donald F. Becker, John J. Tanner   +4 more
doaj   +1 more source

Metformin Treatment or PRODH/POX-Knock out Similarly Induces Apoptosis by Reprograming of Amino Acid Metabolism, TCA, Urea Cycle and Pentose Phosphate Pathway in MCF-7 Breast Cancer Cells

Biomolecules, 2021
It has been considered that proline dehydrogenase/proline oxidase (PRODH/POX) is involved in antineoplastic activity of metformin (MET). The aim of this study is identification of key metabolites of glycolysis, pentose phosphate pathway (PPP ...
Thi Yen Ly Huynh, Ilona Oscilowska, Jorge Sáiz, Magdalena Nizioł, Weronika Baszanowska, Coral Barbas, Jerzy Palka   +6 more
doaj   +1 more source

Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade

Cell Reports, 2016
Proline dehydrogenase (PRODH), which degrades L-proline, resides within the schizophrenia-linked 22q11.2 deletion suggesting a role in disease. Supporting this, elevated L-proline levels have been shown to increase risk for psychotic disorders.
Gregg W. Crabtree, Alan J. Park, Joshua A. Gordon, Joseph A. Gogos   +3 more
doaj   +1 more source

Production of Recombinant Proline Dehydrogenase Enzyme from Pseudomonas fluorescens pf-5 in E. coli System [PDF]

Journal of Sciences, Islamic Republic of Iran, 2011
Proline dehydrogenase (ProDH; 1.5.99.8) belongs to superfamily of amino acid dehydrogenase, which plays a significant role in the metabolic pathway from proline to glutamate. The goal of this research was gene cloning and characterization of ProDH enzyme
E. Omidinia
doaj  

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27)

Frontiers in Pharmacology, 2018
Propolis evokes several therapeutic properties, including anticancer activity. These activities are attributed to the action of polyphenols. Previously it has been demonstrated, that one of the most abundant polyphenolic compounds in ethanolic extracts ...
Katarzyna Celińska-Janowicz, Ilona Zaręba, Urszula Lazarek, Joanna Teul, Michał Tomczyk, Jerzy Pałka, Wojciech Miltyk   +6 more
doaj   +1 more source

Supplementation of 2-Ap, Zn and La Improves 2-Acetyl-1-Pyrroline Concentrations in Detached Aromatic Rice Panicles In Vitro. [PDF]

PLoS ONE, 2016
Aromatic rice is highly prized by consumers worldwide due to its special aromatic character. 2-acetyl-1-pyrroline (2-AP) is considered to be the single most important volatile compound responsible for aroma in aromatic rice.
Zhaowen Mo, Jinxia Huang, Di Xiao, Umair Ashraf, Meiyang Duan, Shenggang Pan, Hua Tian, Lizhong Xiao, Keyou Zhong, Xiangru Tang   +9 more
doaj   +1 more source

Proline dehydrogenase (PRODH) is a differentially expressed gene in brain metastatic human breast cancer.

, 2021
Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer.
openaire   +2 more sources