Results 51 to 60 of about 1,778 (165)
Agriculture, 2022 Proline (Pro) is not only an important osmotic adjustment substance, but it also plays an important role in regulating plant abiotic stress resistance. The maize varieties, Xinxin 2 (low temperature insensitive) and Damin 3307 (low temperature sensitive),
Shiyu Zuo, Jing Li, Wanrong Gu, Shi Wei
doaj +1 more source
High yields of active Thermus thermophilus proline dehydrogenase are obtained using maltose-binding protein as a solubility tag. [PDF]
, 2015 Proline dehydrogenase (ProDH) catalyzes the FAD-dependent oxidation of proline to ¿1-pyrroline-5-carboxylate, the first step of proline catabolism in many organisms.
Huijbers, M.M.E. +2 more
core +1 more source
Mitochondrial NADK2‐dependent NADPH controls tau oligomer uptake in human neurons
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract INTRODUCTION Reduced brain energy metabolism, mitochondria dysfunction, and extracellular tau oligomer buildup characterize Alzheimer's disease (AD), but how these phenomena cooperatively promote neurodegeneration is poorly understood. We now report that tau oligomers (TauOs) pathologically coordinate mitochondrial metabolism with increased ...
Evelyn Pardo +10 more
wiley +1 more source
Molecular and Biochemical Characterization of the proline dehydrogenase of T. cruzi, a possible therapeutical target . [PDF]
, 2010 Os nossos resultados demonstraram a atividade enzimática prolina desidrogenase (PRODH) do produto do gene anotado como codificante de uma prolina oxidase na base dados do genoma de Trypanosoma cruzi.
Lisvane Paes Vieira +1 more
core +1 more source
Computational insights on the hydride and proton transfer mechanisms of L-proline dehydrogenase.
PLoS ONE, 2023 L-Proline dehydrogenase (ProDH) is a flavin-dependent oxidoreductase, which catalyzes the oxidation of L-proline to (S)-1-pyrroline-5-carboxylate. Based on the experimental studies, a stepwise proton and hydride transfer mechanism is supported. According
Ibrahim Yildiz
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 12, Page 4745-4770, 15 June 2026.Abstract figure legend Seasonal changes profoundly reshape honey bee mitochondrial metabolism. In winter, bees shift from complex I (CI)‐ to mitochondrial glycerol‐3‐phosphate dehydrogenase (mG3PDH)‐ and complex II (CII)‐linked respiration. Despite lower CI‐linked respiration ATP production is maintained, suggesting increased energetic efficiency in ...
Adèle Léger +5 more
wiley +1 more source
Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms
Food Frontiers, Volume 7, Issue 3, May 2026.Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang +4 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2016 Plants activate different defense systems to counteract the attack of microbial pathogens. Among them, the recognition of conserved microbial- or pathogen-associated molecular patterns (MAMPs or PAMPs) by pattern-recognition receptors stimulates MAMP- or
Georgina Fabro +2 more
doaj +1 more source
Frontiers in Plant Science, 2023 The demand for healthy foods with high functional value has progressively increased. Carbon nanoparticles (CNPs) have a promising application in agriculture including the enhancement of plant growth.
Riyadh F. Halawani +7 more
doaj +1 more source
Proline dehydrogenase is essential for proline protection against hydrogen peroxide induced cell death [PDF]
, 2012 Proline metabolism has an underlying role in apoptotic signaling that impacts tumorigenesis. Proline is oxidized to glutamate in the mitochondria with the rate limiting step catalyzed by proline dehydrogenase (PRODH). PRODH expression is inducible by p53
Zhu, Weidong +7 more
core +1 more source