Results 91 to 100 of about 11,890 (215)

Pro-opiomelanocortin and ACTH–cortisol dissociation during pediatric cardiac surgery

Endocrine Connections
In critically ill adults, high plasma cortisol in the face of low ACTH coincides with high pro-opiomelanocortin (POMC) levels. Glucocorticoids further lower ACTH without affecting POMC.
Arno Téblick, Ilse Vanhorebeek, Inge Derese, An Jacobs, Renata Haghedooren, Sofie Maebe, Gerdien A Zeilmaker-Roest, Enno D Wildschut, Lies Langouche, Greet Van den Berghe   +9 more
doaj   +1 more source

A proopiomelanocortin‐derived peptide sequence enhances plasma stability of peptide drugs

, 2020
Bioactive peptide drugs hold promise for therapeutic application due to their high potency and selectivity but display short plasma half-life. Examination of selected naturally occurring peptide hormones derived from proteolytic cleavage of the ...
Karin Löw, Roulin, A., Löw, K., Kunz, S., Stefan Kunz, Alexandre Roulin, Roulin A, Löw K, Kunz S   +8 more
core   +1 more source

Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain [PDF]

, 1984
The immunocytochemical distribution of Proopiomelanocortin (POMC) peptides ([beta]-endorphin, ACTH, [alpha]-MSH, 16K fragment) was studied in the brain of the rhesus monkey (Macaca mulatta).
Michael E. Lewis, Henry Khachaturian, S. N. Haber, H. Akil, Haber, Suzanne N., Lewis, Michael E., Akil, Huda, Khachaturian, Henry, Watson, Stanley J., Hf. E. Lewis, Suzanne N. Haber   +10 more
core   +1 more source

Role of the ubiquitin/proteasome system on ACTH turnover in rat corticotropes [PDF]

, 2018
Purpose: A large number of studies has investigated proopiomelanocortin processing in anterior pituitary corticotropes but little is known on proopiomelanocortin/ACTH degradation within these cells.
Cavagnini, Francesco, Francesco Cavagnini, Cassarino, Maria Francesca, Maria Francesca Cassarino, Sesta, Antonella, Francesca Pecori Giraldi, Pecori Giraldi, Francesca, Antonella Sesta   +7 more
core   +1 more source

Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of sardinian alcohol-preferring rats [PDF]

, 2013
[Background]: Evidence obtained in humans and rodents indicates that beta-endorphin (encoded by the proopiomelanocortin [POMC] gene) is critical in the regulation of alcohol drinking behavior.
Ho, Ann, Kreek, Mary Jeanne, Zhou, Yan, García-Gutiérrez, María Salud, Manzanares, Jorge, Carai, Mauro A. M., Femenía, Teresa, Gessa, Gian Luigi, Niikura, Keiichi, García Gutiérrez, María Salud, Colombo, Giancarlo, FEMENIA CANTO, TERESA   +11 more
core   +1 more source

A case of early-onset obesity, hypocortisolism, and skin pigmentation problem due to a novel homozygous mutation in the proopiomelanocortin (POMC) gene in an Indian boy

, 2012
Proopiomelanocortin (POMC) is the polypeptide precursor of several biologically active melanocortin peptides that have important roles in the regulation of food intake and energy homeostasis, adrenal steroidogenesis, melanocyte stimulation, and immune ...
Lee, CY, Poon, DWT, Hung, CN, Chan, AYW, Law, CY   +4 more
core   +1 more source

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

, 2016
NÖRON HÜCRELERİNDE ILE22MET PROOPİOMELANOCORTİN (POMC) MUTASYONUNUN HÜCRESEL ...
Vural, Merve, Yanık, Tülin
core  

PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding

, 2014
Activation of central PPARγ promotes food intake and body weight gain; however, the identity of the neurons that express PPARγ and mediate the effect of this nuclear receptor on energy homeostasis is unknown.
Horvath, Tamas L, Jeong, Jing Kwon, Jing Kwon Jeong, Toda, Chitoku, Lihong Long, Tamas L. Horvath, Horvath, Tamas L., Chitoku Toda, Long, Lihong, Sabrina Diano, Diano, Sabrina   +10 more
core   +1 more source

Role of proopiomelanocortin in preventing miscarriage

, 2017
OBJECTIVE: To compare the distribution of proopiomelanocortin (POMC) in decidua and placenta samples from missed abortion and voluntary termination cases in order to research the effects in the etiology of missed abortion.
Uluer, Elgin T., Atay, Coşkun, Vatansever, Seda, Özçakır, Tayfun, Ozbilgin, Kemal, Kahraman, Burcu   +5 more
core   +1 more source

Anabolic androgenic steroid nandrolone decanoate reduces hypothalamic proopiomelanocortin mRNA levels

, 2003
Supratherapeutical doses of anabolic androgenic steroids (AASs) have dramatic effects on metabolism in humans, and also inhibit feeding and reduce the rate of body weight gain in rats.
Jonas Lindblom, Lindblom, Jonas,, Nyberg, Fred,, Fred Nyberg, Bergström, Lena,, Kindlundh, Anna,, Wikberg, Jarl,, Lena Bergström, Jarl E.S Wikberg, Anna M.S Kindlundh   +9 more
core   +1 more source