Results 101 to 110 of about 19,002 (275)

Alk‐Fam150b (augmentor α) expression in the paraventricular nucleus of the mouse hypothalamus at molecular resolution, and its sensitivity to acute stress

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
In this study, Laurent Gueissaz and his colleagues use cell‐resolved molecular profiling and in situ hybridization to characterize cellular underpinnings of augmentor α‐ALK signaling in the paraventricular nucleus of the mouse hypothalamus. They also show that acute stress affects the transcription of augmentor α but not ALK, which can have functional ...
Laurent Gueissaz   +4 more
wiley   +1 more source

Withdrawal of dietary phytoestrogens in adult male rats affects hypothalamic regulation of food intake, induces obesity and alters glucose metabolism [PDF]

open access: yes, 2015
The absence of phytoestrogens in the diet during pregnancy has been reported to result in obesity later in adulthood. We investigated whether phytoestrogen withdrawal in adult life could alter the hypothalamic signals that regulate food intake and affect
Alzamendi, A.   +6 more
core   +1 more source

The role of accessory proteins and co‐factors in regulation of melanocortin‐4 receptor signalling: An update

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract The melanocortin‐4 receptor (MC4R) is a G protein‐coupled receptor with an essential role in appetite suppression and energy homeostasis. Genetic mutations in the receptor and components of its signalling pathway that cause obesity in humans, dogs and rodent models have revealed important insights into how the receptor signals and what ...
Aqfan Jamaluddin   +3 more
wiley   +1 more source

Biochemical characterization of proopiomelanocortin variants in human and owls [PDF]

open access: yes, 2015
In humans the proopiomelanocortin (POMC) gene is located on the short arm of the chromosome 2 at the 23.3 position and encodes a 39kDa peptide with 241 amino acids. This peptide is the precursor of the proopiomelanocortin prohormone and it is produced in
SAINT-ROCH, A.
core  

Cannabinoid CB2 Receptors Contribute to Upregulation of β-endorphin in Inflamed Skin Tissues by Electroacupuncture [PDF]

open access: yes, 2011
Background: Electroacupuncture (EA) can produce analgesia by increasing the β-endorphin level and activation of peripheral μ-opioid receptors in inflamed tissues.
Tang-Feng Su   +8 more
core   +1 more source

Female rat hippocampal cell density after conditioned place preference [PDF]

open access: yes, 2014
The hippocampus is important for learning tasks, such as conditioned place preference (CPP), which is widely used as a model for studying the reinforcing effects of drugs with dependence liability.
Babakordi, F.   +3 more
core  

Activation of Brainstem Pro-opiomelanocortin Neurons Produces Opioidergic Analgesia, Bradycardia and Bradypnoea.

open access: yesPLoS ONE, 2016
Opioids are widely used medicinally as analgesics and abused for hedonic effects, actions that are each complicated by substantial risks such as cardiorespiratory depression.
Serena Cerritelli   +4 more
doaj   +1 more source

Behavioral and pharmacological characterization of a mouse model of palatable diet alternation [PDF]

open access: yes, 2017
Obesity and eating disorders represent a severe problem in Western societies. Both the increased availability of highly palatable foods and dieting are major risk factors contributing to the epidemic disorders of feeding. The purpose of this study was to
Schlain, Gabrielle Star
core  

Recent advances in understanding Cushing disease: resistance to glucocorticoid negative feedback and somatic USP8 mutations [PDF]

open access: yes, 2017
Cushing’s disease is a rare disease with a characteristic phenotype due to significant hypercortisolism driven by over-secretion of adrenocorticotropic hormone and to high morbidity and mortality if untreated.
A Faesen   +80 more
core   +2 more sources

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons

open access: yesMolecular Metabolism, 2019
Objective: Reelin (RELN) is a large glycoprotein involved in synapse maturation and neuronal organization throughout development. Deficits in RELN signaling contribute to multiple psychological disorders, such as autism spectrum disorder, schizophrenia ...
Brandon L. Roberts   +19 more
doaj   +1 more source

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