Results 111 to 120 of about 19,002 (275)

Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior [PDF]

, 2017
Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V).
Barahona, María José, Elizondo Vega, Roberto, García Robles, María de los Ángeles, Martinez, Fernando, Millán, Carola, Ordenes, Patricio, Recabal, Antonia, Salgado, Magdiel, Sepúlveda, Fernando, Uranga, Romina Maria, Uribe, Elena   +10 more
core   +1 more source

Proopiomelanocortin, Its Derived Peptides, and the Skin

Journal of Investigative Dermatology, 1996
Proopiomelanocortin (POMC) is a protein synthesized predominately in the pituitary gland but also in a variety of other tissues, including the skin. Through enzyme-mediated cleavage that varies among cell types, POMC can give rise to at least eight distinct peptides whose biologic roles are incompletely delineated.
Wintzen, Marjolein, Gilchrest, Barbara A.   +1 more
openaire   +2 more sources

CNS Control of Glucose Metabolism: Response to Environmental Challenges [PDF]

, 2013
Over the last 15 years, considerable work has accumulated to support the role of the CNS in regulating postprandial glucose levels. As discussed in the first section of this review, the CNS receives and integrates information from afferent neurons ...
Arble, Deanna M., Sandoval, Darleen A.
core   +1 more source

PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders. [PDF]

, 2016
Prohormone convertase 1/3, encoded by the PCSK1 gene, is a serine endoprotease that is involved in the processing of a variety of proneuropeptides and prohormones. Humans who are homozygous or compound heterozygous for loss-of-function mutations in PCSK1

core   +2 more sources

Pro-opiomelanocortin and ACTH–cortisol dissociation during pediatric cardiac surgery

Endocrine Connections
In critically ill adults, high plasma cortisol in the face of low ACTH coincides with high pro-opiomelanocortin (POMC) levels. Glucocorticoids further lower ACTH without affecting POMC.
Arno Téblick, Ilse Vanhorebeek, Inge Derese, An Jacobs, Renata Haghedooren, Sofie Maebe, Gerdien A Zeilmaker-Roest, Enno D Wildschut, Lies Langouche, Greet Van den Berghe   +9 more
doaj   +1 more source

Arcuate nucleus homeostatic systems reflect blood leptin concentration but not feeding behaviour during scheduled feeding on a high-fat diet in mice [PDF]

, 2017
Acknowledgements T.B. was funded by a CASE studentship from the BBSRC and AstraZeneca. J.B. was a summer student from Bordeaux Sciences Agro and funded by student laboratory experience grant from the British Society of Neuroendocrinology. The authors are
Bake, T., Baron, J., Duncan, J. S., Mercer, J. G., Morgan, D. G. A.   +4 more
core   +1 more source

Expression of two proopiomelanocortin genes in the pituitary gland ofXenopus laevis:complete structures of the two preprohormones [PDF]

, 1986
Gerard J.M. Martens
openalex   +1 more source

Polymorphic Mucocutaneous Eruption and Septic Shock in a 75‐Year‐Old Man

JEADV Clinical Practice, Volume 5, Issue 1, Page 323-325, March 2026.
Sweta Subhadarshani, Brad R. Woodie, Kerith E. Spicknall   +2 more
wiley   +1 more source

Liquid Chromatography-Mass Spectrometry Detection of Corticotropin-Releasing Hormone and Proopiomelanocortin-Derived Peptides in Human Skin¹ [PDF]

, 2000
Andrzej Słomiński, Andrzej Szczesniewski, Jacobo Wortsman   +2 more
openalex   +1 more source

Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]

, 2018
BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core