Results 121 to 130 of about 19,002 (275)

Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective [PDF]

, 2019
The melanocortin-4 receptor (MC4R) can be endogenously activated by binding of melanocyte-stimulating hormones (MSH), which mediates anorexigenic effects. In contrast, the agouti-related peptide (AgRP) acts as an endogenous inverse agonist and suppresses
Biebermann, Heike, Cerdá-Reverter, José Miguel, Heyder, Nicolas, Kleinau, Gunnar, Krude, Heiko, Kwiatkowski, Dennis, Kühnen, Peter, Scheerer, Patrick, Soletto, Lucia, Speck, David, Szczepek, Michal   +10 more
core   +1 more source

637. Intrathecal Electroporation of Doxycycline Regulated Proopiomelanocortin Gene for the Neuropathic Pain Therapy in CCI Rats [PDF]

, 2004

openalex   +1 more source

Evidence Suggesting That Galanin (GAL), Melanin-Concentrating Hormone (MCH), Neurotensin (NT), Proopiomelanocortin (POMC) and Neuropeptide Y (NPY) Are Targets of Leptin Signaling in the Hypothalamus [PDF]

, 1998
A. Sahu
openalex   +1 more source

Melanocortin‐4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats [PDF]

, 2023
C. P. Jerjen, Sampath Kumaran, Annette Liesegang, Evelyn Hall, Brigitta Wichert, Bianca Haase   +5 more
openalex   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Interleukin-11 Stimulates Proopiomelanocortin Gene Expression and Adrenocorticotropin Secretion in Corticotroph Cells: Evidence for a Redundant Cytokine Network in the Hypothalamo-Pituitary-Adrenal Axis* [PDF]

, 1999
Christoph J. Auernhammer, Шломо Мелмед   +1 more
openalex   +1 more source

Differential regulation of proopiomelanocortin messenger ribonucleic acid in the pars distalis and pars intermedia of the pituitary gland after prolonged hypoxemia in fetal sheep. [PDF]

, 1996
GA Braems, Stephen G. Matthews, John Challis   +2 more
openalex   +1 more source

Generation of an isogenic iPSC line via CRISPR correction of the POMC:W84X mutation for monogenic obesity modeling

Stem Cell Research
We report the generation of a genetically corrected induced pluripotent stem cell (iPSC) line, BIHi261-A-1, derived from the patient-specific iPSC line BIHi261-A carrying a homozygous truncating mutation in the POMC gene (POMC:W84X). This mutation causes
Katarzyna A. Ludwik, Valeria Fernandez Valone, Regina Jahn, Sabine Jyrch, Lara Lechner, Peter Kühnen, Harald Stachelscheid   +6 more
doaj   +1 more source

Expression of GalR1 and GalR2 Galanin Receptor Messenger Ribonucleic Acid in Proopiomelanocortin Neurons of the Rat Arcuate Nucleus: Effect of Testosterone* [PDF]

, 2000
Sébastien G. Bouret, Vincent Prévot, Dominique Croix, Andrew D. Howard, Estelle Habert-Ortoli, Sylvie Jégou, Hubert Vaudry, Jean‐Claude Beauvillain, Valérie Mitchell   +8 more
openalex   +1 more source

Hypo-cortisolism, early onset obesity and liver disease in a child with homozygous proopiomelanocortin mutation

, 2021
Rajesh Joshi, Krishna Malagi
openalex   +2 more sources