Results 141 to 150 of about 8,881 (183)

Molecular Cloning of Lungfish Proopiomelanocortin cDNA

General and Comparative Endocrinology, 1999
To investigate the evolution of proopiomelanocortin (POMC) from fish to tetrapods, nucleotide sequence of POMC cDNA from a lobe-finned fish, the African lungfish, was determined. POMC cDNA was prepared from lungfish pituitary glands. The POMC cDNA is composed of 1114 bp, excluding a poly-A tail, and encodes 255 amino acids (aa) including a signal ...
Y, Amemiya, A, Takahashi, H, Meguro, H, Kawauchi   +3 more
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From Proopiomelanocortin to Cancer

Annals of the New York Academy of Sciences, 1993
Melanophore-stimulating hormones (MSHs) are produced from a common precursor called proopiomelanocortin (POMC). These peptides have been at the center of studies on the prohormone theory since 1967. The recent discovery of endoproteases which can convert POMC to MSHs is having more biological implications than previously imagined, most particularly for
M, Mbikay, N G, Seidah, M, Chretien
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Ectopic Secretion of Peptides of the Proopiomelanocortin Family

Endocrinology and Metabolism Clinics of North America, 1991
A wide spectrum of clinical and biochemical presentations characterize ectopic POMC syndrome. It is presently postulated that ectopic POMC production results from increased expression of the activity of a POMC gene normally occurring in a variety of tissues outside the pituitary gland.
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Proopiomelanocortin-derived peptides in mice with motoneurone disease

Neuroscience Letters, 1989
beta-Endorphin and alpha-melanotropin immunoreactivity was detected in motor nerves in histological sections of murine skeletal muscle, using the peroxidase-antiperoxidase technique. In mice of the wobbler strain, which can inherit motoneurone disease, a significantly higher proportion of the intramuscular nerves in soleus, extensor digitorum longus ...
S, Hughes, M E, Smith
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PROOPIOMELANOCORTIN‐DERIVED PEPTIDES IN THE IMMUNE SYSTEM

Clinical Endocrinology, 1985
SUMMARYCells of the immune system have recently been recognized as a source of the proopiomelanocortin (POMC)‐derived peptides, ACTH and endorphins, and their receptors. In this review, the nature of the immunoregulatory and hypothalamic signals which elicit the production of these leukocyte‐derived hormones is discussed.
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Proopiomelanocortin and Related Hormones

2010
The cutaneous proopiomelanocortin (POMC) system is an important regulatory system, which controls pigmentation, inflammation, and the stress response of the skin. Based on their potent melanotropic effects, selected melanocortin peptides derived from POMC have been tested in the past for their efficacy in vitiligo.
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Proopiomelanocortin gene expression in man

2003
Proopiomelanocortin (POMC) is the polypeptide precursor to ACTH and several other biologically active peptides.
Yves de Keyzer, Marie-Laure Raffin-Sanson, Xavier Bertagna   +2 more
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Proopiomelanocortin and the Melanocortin Peptides

2000
The “melanophore stimulants” were discovered about 80 yr ago when, with surgical ablation experiments, the pituitary gland was shown to be involved in the control of skin color of amphibia. The pars intermedia was soon recognized as the origin of the biological principle, then also named “intermedin,” which induced darkening of amphibian skin (for a ...
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Molecular evolution of proopiomelanocortin in fish

2003
Proopiomelanocortin (POMC) is a common precursor protein for several hormonal peptides, such as adrenocorticotropin, β-lipotropin, α-, β-, γ -melanotropins (MSHs), and β-endorphin secreted from the pituitary gland of vertebrates. These POMC products exhibit a variety of physiological functions, which are associated with stress response and ...
Akiyoshi Takahashi, Yutaka Amemiya, Masumi Nozaki, Stacia A. Sower, Hiroshi Kawauchi   +4 more
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Role of Proopiomelanocortin in Preventing Miscarriage.

The Journal of reproductive medicine, 2018
To compare the distribution of proopiomelanocortin (POMC) in decidua and placenta samples from missed abortion and voluntary termination cases in order to research the effects in the etiology of missed abortion.Decidual materials were collected from patients who were diagnosed with missed abortion (n=19) and legal voluntary termination cases (n=15 ...
Kemal, Ozbilgin, Burcu, Kahraman, Coşkun, Atay, Seda, Vatansever, Elgin T, Uluer, Tayfun, Özçakır   +5 more
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