Results 71 to 80 of about 8,881 (183)

Pro-opiomelanocortin and ACTH–cortisol dissociation during pediatric cardiac surgery

Endocrine Connections
In critically ill adults, high plasma cortisol in the face of low ACTH coincides with high pro-opiomelanocortin (POMC) levels. Glucocorticoids further lower ACTH without affecting POMC.
Arno Téblick, Ilse Vanhorebeek, Inge Derese, An Jacobs, Renata Haghedooren, Sofie Maebe, Gerdien A Zeilmaker-Roest, Enno D Wildschut, Lies Langouche, Greet Van den Berghe   +9 more
doaj   +1 more source

Generation of an isogenic iPSC line via CRISPR correction of the POMC:W84X mutation for monogenic obesity modeling

Stem Cell Research
We report the generation of a genetically corrected induced pluripotent stem cell (iPSC) line, BIHi261-A-1, derived from the patient-specific iPSC line BIHi261-A carrying a homozygous truncating mutation in the POMC gene (POMC:W84X). This mutation causes
Katarzyna A. Ludwik, Valeria Fernandez Valone, Regina Jahn, Sabine Jyrch, Lara Lechner, Peter Kühnen, Harald Stachelscheid   +6 more
doaj   +1 more source

Pro-Opiomelanocortin and Melanocortin Receptor 3 and 4 Mutations in Genetic Obesity

Biomolecules
Genetic obesity results from loss-of-function mutations, including those affecting the leptin–melanocortin system, which regulates body weight. Pro-opiomelanocortin (POMC)-derived neurohormones act as ligands for melanocortin receptors (MCRs), regulating
Tulin Yanik, Seyda Tugce Durhan
doaj   +1 more source

Acquired isolated ACTH deficiency co-occurrence with breast cancer irrespective of paraneoplastic syndrome: coincidence or inevitability

Endocrinology, Diabetes & Metabolism Case Reports
A 52-year-old female patient with breast cancer presented with a history of fatigue and malaise 1 year prior. She was diagnosed with isolated adrenocorticotropic hormone (ACTH) deficiency (IAD) on endocrinological examination.
Shin Urai, Hironori Bando, Mei Nakatsuji, Masaaki Yamamoto, Hidenori Fukuoka, Genzo Iguchi, Wataru Ogawa   +6 more
doaj   +1 more source

Electroacupuncture reduces obesity by improving metabolism and up-regulating expression of hypothalamic Sirtuin 1 and proopiomelanocortin in obese rats

针刺研究, 2019
Objective To observe the effect of electroacupuncture(EA)on expression of hypothalamic sirtuin 1(SIRT1)and proopiomelanocortin(POMC),and body weight,food-intake,blood glucose,and blood lipid levels in obese rats,so as to explore its mechanisms underlying
HUANG Qi, CHEN Rui, CHEN Li, LIANG Feng-xia, HE Wen-juan, PENG Miao, LI Lun   +6 more
doaj  

Angiotensin-(1-7) Activates Proopiomelanocortin Neurons in the Arcuate Nucleus. [PDF]

Hypertension
Vernail VL, Mehay DL, Kimbark KD, Tanner JA, Bingaman SS, Silberman Y, Arnold AC.   +6 more
europepmc   +1 more source

Effect of Normal Level Endocrine Hormones and Hypothalamic Neuropeptides on Obesity in Women of Childbearing Age. [PDF]

J Obes
Tang Y, Zhang X, Fan L, Li C, Guo Y, Du F, Wang W.   +6 more
europepmc   +1 more source

Effect of Centrally Administered Neuropeptide Y and α-Melanocyte-stimulating Hormone on Water Intake in Chicks. [PDF]

J Poult Sci
Dialoke NG, Murata K, Zhang Y, Taniguchi Y, Hinomoto SI, Takegaki J, Saneyasu T, Honda K.   +7 more
europepmc   +1 more source

Evaluation of the Relationship Between Orexin A, Peptide YY, AgRP, and POMC Levels and Sleep Disorders in Children with Malnutrition. [PDF]

Nutrients
Ergani AC, Tezcan ME, Can Ü, Arslan Kılıçoğlu E.   +3 more
europepmc   +1 more source

The proopiomelanocortin gene of Xenopus laevis [PDF]

, 1991
120 p.
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