Results 51 to 60 of about 19,002 (275)
Equine Veterinary Education, EarlyView.Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken +5 more
wiley +1 more source
Impaired processing of proopiomelanocortin in corticotroph macroadenomas. [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1996 The regulation and secretion of the ACTH precursors POMC and pro-ACTH were assessed directly using a 2-site immunoradiometric assay in six patients with pituitary macroadenomas (> or = 1.2 cm in diameter) and 27 patients with Cushing's disease due to a microadenoma.
Gibson, S +7 more
openaire +3 more sources
Effects of Variants in and Genes on Growth, Carcass, and Meat Quality Traits in Rabbits [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 Appetite-related neuropeptides proopiomelanocortin (POMC) and Neuropeptide Y (NPY) are essential for regulating feeding behavior and energy homeostasis.
Wen-Chao Liu +4 more
doaj +1 more source
Setmelanotide in Bardet‐Biedl Syndrome: A Case Report
Pediatric Dermatology, EarlyView.ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith +2 more
wiley +1 more source
Biomimetic proopiomelanocortin suppresses capsaicin-induced sensory irritation in humans
Research in Pharmaceutical Sciences, 2016 Sensitive skin is a frequently mentioned cosmetic complaint. Addition of a biomimetic of neuromediator has recently appeared as a promising new way to cure skin care product problems.
Sayed Ali Fatemi +3 more
doaj +1 more source
Nuclear Receptors as Regulators of Pituitary Corticotroph Pro-Opiomelanocortin Transcription
Cells, 2020 The hypothalamic–pituitary–adrenal (HPA) axis plays a critical role in adaptive stress responses and maintaining organism homeostasis. The pituitary corticotroph is the central player in the HPA axis and is regulated by a plethora of hormonal and stress ...
Dongyun Zhang, Anthony P. Heaney
doaj +1 more source
Trilogy Development of Proopiomelanocortin Neurons From Embryonic to Adult Stages in the Mice Retina
Frontiers in Cell and Developmental Biology, 2021 Proopiomelanocortin-positive amacrine cells (POMC ACs) were first discovered in adult mouse retinas in 2010; however, the development of POMC-ACs has not been studied.
Xuhong Zhang +10 more
doaj +1 more source
The role of insulin receptor substrate 2 in hypothalamic and beta cell function [PDF]
, 2005 Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in beta cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Al-Qassab, H +19 more
core
Circulating phagocytes: The ancient and conserved interface between immune and neuroendocrine function [PDF]
, 2017 Immune and neuroendocrine functions display significant overlap in highly divergent and evolutionarily distant models such as molluscs, crustaceans, insects and mammals.
MALAGOLI, Davide +3 more
core +1 more source
Zoologica Scripta, EarlyView.ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi +10 more
wiley +1 more source