Results 31 to 40 of about 10,743 (219)
Frontiers in Pharmacology, 2021 Erythropoietin (EPO) receptor (EPOR) determines EPO response. High level EPOR on erythroid progenitor cells gives rise to EPO regulated production of red blood cells. Animal models provide evidence for EPO activity in non-hematopoietic tissue mediated by
Soumyadeep Dey +2 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2018 We tested the hypotheses that steroidogenic factor (SF)-1 neurons in the hypothalamic ventromedial nucleus (VMN) provide sexually disparate, endocannabinoid (EC)- and diet-sensitive glutamatergic input onto proopiomelanocortin (POMC) neurons ...
Carolina Fabelo +8 more
doaj +1 more source
Comparative study of gp130 cytokine effects on corticotroph AtT-20 cells - Redundancy or specificity of neuroimmunoendocrine modulators? [PDF]
, 2004 Objective: This comparative in vitro study examined the effects of all known gp130 cytokines on murine corticotroph AtT-20 cell function. Methods: Cytokines were tested at equimolar concentrations from 0.078 to 10 nM.
Kopp, F. B. +9 more
core +1 more source
The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments [PDF]
Archives of Endocrinology and MetabolismThe hypothalamus is a master regulator of energy balance in the body. First-order hypothalamic neurons localized in the arcuate nucleus sense systemic signals that indicate the energy stores in the body.
Bruna Bombassaro +2 more
doaj +1 more source
Serum kisspeptin and proopiomelanocortin in cystic fibrosis: a single study
Scientific Reports, 2022 The determination of hormonal biomarkers is of increasing interest in many diseases, including cystic fibrosis (CF). Hormones that have not been estimated and described so far in CF include kisspeptin (KISS) and proopiomelanocortin (POMC), which are ...
Sabina Galiniak +3 more
doaj +1 more source
, 2013 Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Nunez, Cristina +13 more
core +1 more source
Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of sardinian alcohol-preferring rats [PDF]
, 2013 [Background]: Evidence obtained in humans and rodents indicates that beta-endorphin (encoded by the proopiomelanocortin [POMC] gene) is critical in the regulation of alcohol drinking behavior.
Ho, Ann +11 more
core +1 more source
Impaired processing of proopiomelanocortin in corticotroph macroadenomas. [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1996 The regulation and secretion of the ACTH precursors POMC and pro-ACTH were assessed directly using a 2-site immunoradiometric assay in six patients with pituitary macroadenomas (> or = 1.2 cm in diameter) and 27 patients with Cushing's disease due to a microadenoma.
Gibson, S +7 more
openaire +3 more sources
Activation of the ARCPOMC→MeA Projection Reduces Food Intake
Frontiers in Neural Circuits, 2020 Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) plays an essential role in the control of food intake and energy expenditure.
Eunjin Kwon +4 more
doaj +1 more source
Uncoupling of proopiomelanocortin (POMC) fragments is related to self-injury [PDF]
, 2000 Proopiomelanocortin (POMC) contains several interesting, behaviorally active peptides. Release patterns of these fragments have been related to bizarre episodes of self-injurious behavior (SIB) among autistic individuals.
Hetrick, William +4 more
core +1 more source