Results 31 to 40 of about 11,890 (215)

Selected hormonal and neurotransmitter mechanisms regulating feed intake in sheep

Animal, 2010
Appetite control is a major issue in normal growth and in suboptimal growth performance settings. A number of hormones, in particular leptin, activate or inhibit orexigenic or anorexigenic neurotransmitters within the arcuate nucleus of the hypothalamus,
J.L. Sartin, J.A. Daniel, B.K. Whitlock, R.R. Wilborn   +3 more
doaj   +1 more source

Increase of proopiomelanocortin-related peptides during subjective menopausal flushes.

, 1984
The present study reports the plasma levels of gonadotropins (luteinizing hormone, follicle-stimulating hormone), proopiomelanocortin-related peptides (adrenocorticotropic hormone, beta-endorphin, and beta-lipotropin), and cortisol in eight menopausal ...
Volpe A, GENAZZANI, ANDREA, Alessandrini G., Petraglia F, Facchini V, Facchinetti F   +5 more
core   +2 more sources

Endocannabinoid Signaling at Hypothalamic Steroidogenic Factor-1/Proopiomelanocortin Synapses Is Sex- and Diet-Sensitive

Frontiers in Molecular Neuroscience, 2018
We tested the hypotheses that steroidogenic factor (SF)-1 neurons in the hypothalamic ventromedial nucleus (VMN) provide sexually disparate, endocannabinoid (EC)- and diet-sensitive glutamatergic input onto proopiomelanocortin (POMC) neurons ...
Carolina Fabelo, Jennifer Hernandez, Rachel Chang, Sakara Seng, Natalia Alicea, Sharon Tian, Kristie Conde, Edward J. Wagner, Edward J. Wagner   +8 more
doaj   +1 more source

The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments [PDF]

Archives of Endocrinology and Metabolism
The hypothalamus is a master regulator of energy balance in the body. First-order hypothalamic neurons localized in the arcuate nucleus sense systemic signals that indicate the energy stores in the body.
Bruna Bombassaro, Eliana P. Araujo, Licio A. Velloso   +2 more
doaj   +1 more source

Activation of the ARCPOMC→MeA Projection Reduces Food Intake

Frontiers in Neural Circuits, 2020
Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) plays an essential role in the control of food intake and energy expenditure.
Eunjin Kwon, Eunjin Kwon, Young-Hwan Jo, Young-Hwan Jo, Young-Hwan Jo   +4 more
doaj   +1 more source

GABA Release from Proopiomelanocortin Neurons [PDF]

The Journal of Neuroscience, 2004
Neural networks controlling food intake and energy homeostasis clearly involve proopiomelanocortin (POMC) neurons and their peptide transmitters. α-melanocyte-stimulating hormone from arcuate POMC neurons potently reduces food intake, whereas arcuate neuropeptide Y (NPY) neurons act in opposition to stimulate food intake.
Shane T, Hentges, Mitsuru, Nishiyama, Linda S, Overstreet, Mary, Stenzel-Poore, John T, Williams, Malcolm J, Low   +5 more
openaire   +2 more sources

The role of insulin receptor substrate 2 in hypothalamic and β cell function [PDF]

, 2005
Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in β cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Hisadome, Kazunari, Choudhury, Agharul I., Smith, Mark A., Simmgen, M., Diakonov, Ivan, Allison W. Xu, Bedford, D.C., Michael L.J. Ashford, Speakman, J.R., Helen Heffron, Bedford, David C., Selman, Colin, Marc Claret, Xu, Allison W., Kazunari Hisadome, Claret, Marc, MacColl, Gavin, Bell, Jimmy D., Speakman, John R., Heffron, H., Melanie Clements, Barsh, Gregory S., Agharul I. Choudhury, Choudhury, A.I., Heffron, Helen, Hind Al-Qassab, Xu, A.W., Vazira Moosajee, Withers, D.J., Hisadome, K., Barsh, G.S., Clements, Melanie, Mark A. Smith, Ashford, Michael L.J.; id_orcid, Withers, Dominic J., Moosajee, Vazira, Dominic J. Withers, Claret, M., MacColl, G., Selman, C., Ivan Diakonov, Al-Qassab, H., Al-Qassab, Hind, Moosajee, V., Gavin MacColl, Simmgen, Marcus, Bell, J.D., Smith, M.A., Ashford, M.L.J., Gregory S. Barsh, Diakonov, I., Batterham, R.L., David C. Bedford, Batterham, Rachel L., Colin Selman, Jimmy D. Bell, Clements, M., Marcus Simmgen, Rachel L. Batterham, John R. Speakman   +59 more
core   +1 more source

Impaired processing of proopiomelanocortin in corticotroph macroadenomas. [PDF]

The Journal of Clinical Endocrinology & Metabolism, 1996
The regulation and secretion of the ACTH precursors POMC and pro-ACTH were assessed directly using a 2-site immunoradiometric assay in six patients with pituitary macroadenomas (> or = 1.2 cm in diameter) and 27 patients with Cushing's disease due to a microadenoma.
Gibson, S, Ray, DW, Crosby, SR, Dornan, TL, Jennings, AM, Bevan, JS, Davis, JRE, White, A.; id_orcid 0000-0002-7686-2884   +7 more
openaire   +3 more sources

Serum kisspeptin and proopiomelanocortin in cystic fibrosis: a single study

Scientific Reports, 2022
The determination of hormonal biomarkers is of increasing interest in many diseases, including cystic fibrosis (CF). Hormones that have not been estimated and described so far in CF include kisspeptin (KISS) and proopiomelanocortin (POMC), which are ...
Sabina Galiniak, Rafał Podgórski, Marta Rachel, Artur Mazur   +3 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source