Results 51 to 60 of about 8,235 (150)
Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]
, 2019 The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto +5 more
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Exosome nanovesicles: biomarkers and new strategies for treatment of human diseases
MedComm, Volume 5, Issue 8, August 2024.• Updated review of recent exosomes in liquid biopsy and disease treatment applications • Recent advances in the use of exosomes as biomarkers in disease applications • Therapies and efficacy of engineered exosome applications • Impact of exosomes on precision medicine and personalized treatment Abstract Exosomes are nanoscale vesicles of cellular ...
Chuan Xu +9 more
wiley +1 more source
QUANTITATIVE STUDIES ON THE PROPERDIN-COMPLEMENT SYSTEM [PDF]
The Journal of Experimental Medicine, 1956 Quantitative methods have been developed for the estimation of C'3 and properdin. With these methods, the kinetics of the over-all reaction between properdin, zymosan, and C'3 were investigated. The reaction followed first order kinetics, provided zymosan was in excess, and the serum not diluted beyond 1/4.
openaire +6 more sources
Journal of Neuroscience Research, Volume 102, Issue 7, July 2024.Proteoglycans are important multifunctional components of the central and peripheral nervous systems and represent a diverse group of specialized proteins that stabilize and functionalize these tissues. Abstract Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse functional roles, this study examined how these control ...
James Melrose
wiley +1 more source
Complement inhibition in paroxysmal nocturnal hemoglobinuria: From biology to therapy
International Journal of Laboratory Hematology, Volume 46, Issue S1, Page 43-54, May 2024.Abstract Complement inhibitors are the mainstay of paroxysmal nocturnal hemoglobinuria (PNH) treatment. The anti‐C5 monoclonal antibody eculizumab was the first treatment to improve hemolysis, thrombotic risk, and survival in PNH although at the price of a life‐long intravenous fortnightly drug.
Francesco Versino, Bruno Fattizzo
wiley +1 more source
, 2007 thesisUnder carefully controlled conditions, bovine serum properdin was isolated and partially purified by employing cold ethanol fractionation procedures.
Miya, Fred
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Journal of Fish Biology, Volume 104, Issue 4, Page 1091-1111, April 2024.Abstract Florida pompano (Trachinotus carolinus) are a species of growing interest for commercial aquaculture. Effective health monitoring is crucial to the successful growout of the species, and prophylactic and therapeutic use of chemicals and antibiotics has been the traditional strategy for promoting stock health.
Ashley N. Morgan +5 more
wiley +1 more source
Properdin Levels in Splenectomized Persons
Experimental Biology and Medicine, 1959 SummaryProperdin titers were definitely lower in 105 splenectomized persons than in 113 normal; healthy subjects. Within the splenectomized group, there was no correlation between properdin level and age of individual, age at splenectomy, and years post-splenectomy.
Harold N. Carlisle, Samuel Saslaw
openaire +3 more sources
Properdin: A Novel Target for Neuroprotection in Neonatal Hypoxic-Ischemic Brain Injury [PDF]
, 2019 Background: Hypoxic-ischemic (HI) encephalopathy is a major cause of neonatal mortality and morbidity, with a global incidence of 3 per 1,000 live births.
Agha-Shah, Q +5 more
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, 2008 thesisIn vitro experiments were undertaken to determine the role of compliment, properdin and antibody in the phagocytosis and cytopepsis of Histoplasma capsulatum by peritoneal macrophages from normal and immunized mice.
Wu, William Gay.
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