Results 101 to 110 of about 3,903,665 (206)
Clinical Transplantation, Volume 39, Issue 5, May 2025.ABSTRACT Background Human donor kidneys release (pro)renin, erythropoietin (EPO), active vitamin D, and urodilatin during normothermic machine perfusion (NMP). However, whether the endocrine function of donor kidneys is associated with post‐transplant kidney function is unclear.
Hui Lin +9 more
wiley +1 more source
118. THE PRORENIN RECEPTOR/PLZF PATHWAY IN HUMAN AMNION
, 2010 Prorenin, despite being inactive, is the major form of renin found in amniotic fluid and reproductive tissues. Prorenin becomes active if it binds to the novel prorenin receptor (ATP6AP2).
A. L. Conquest +4 more
core +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2016 Akihiro Tojo,1 Satoshi Kinugasa,1 Toshiro Fujita,2 Christopher S Wilcox3 1Division of Nephrology and Endocrinology, 2Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan; 3Division of Nephrology and Hypertension ...
Tojo A, Kinugasa S, Fujita T, Wilcox CS
doaj
Plasma Soluble (Pro)renin Receptor Reflects Renal Damage.
PLoS ONE, 2016 Background(Pro)renin receptor [(P)RR], a specific receptor for renin and prorenin, was identified as a member of the renin-angiotensin system (RAS). (P)RR is cleaved by furin, and soluble (P)RR [s(P)RR] is secreted into the extracellular space.
Naro Ohashi +13 more
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Activation of the (pro)renin receptor (PRR) up-regulates the expression of profibrotic genes in the kidney and heart. We aimed to investigate the role of PRR in hepatic fibrogenesis.
Yun-Cheng Hsieh +10 more
doaj +1 more source
Health Science Reports, Volume 8, Issue 3, March 2025.ABSTRACT Background and Aims Hypertension exacerbates cardiovascular risks in patients with type 1 diabetes mellitus (T1DM), necessitating effective blood pressure (BP) management. Vitamin D deficiency is common in T1DM patients and is associated with an increased risk of cardiovascular diseases.
Rasoul Ebrahimi +4 more
wiley +1 more source
Prorenin Accumulation and Activation in Human Endothelial Cells
, 2001 —ACE inhibitors improve endothelial dysfunction, possibly by blocking endothelial angiotensin production. Prorenin, through its binding and activation by endothelial mannose 6-phosphate (M6P) receptors, may contribute to this production.
Maarten A. D. H. Schalekamp +8 more
core +1 more source
(Pro)renin Receptor And Its Soluble Form in Metabolic Dysfunction: Friend or Foe? [PDF]
, 2023 (Pro)renin receptor is component of the renin angiotensin system which has been shown to be involved in several physiological and pathophysiological processes including blood pressure regulation and hypertension, water and electrolyte balance, kidney ...
Arthur, Gertrude
core +1 more source
(Pro)renin Receptor in Kidney Development and Disease
International Journal of Nephrology, 2011 The renin-angiotensin system (RAS), a key regulator of the blood pressure and fluid/electrolyte homeostasis, also plays a critical role in kidney development. All the components of the RAS are expressed in the developing metanephros.
Renfang Song, Ihor V. Yosypiv
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Wnt signalosomes: What we know that we do not know
BioEssays, Volume 47, Issue 2, February 2025.Wnt signaling occurs through a “signalosome” receptor complex, driven by oligomerization of the adaptor, Disheveled (Dvl). Both endocytosis and condensate formation have been proposed to mediate signalosome formation. Under pathological conditions, signalosomes may form in a Wnt ligand‐independent manner.
Heather Hartmann +6 more
wiley +1 more source