Results 21 to 30 of about 7,100 (207)
The role of inflammation in the pathogenesis of type 2 diabetes mellitus (T2DM) and its associated complications is increasingly recognized. The resolution of inflammation is actively regulated by endogenously produced lipid mediators such as lipoxins ...
Emma eBorgeson, Catherine eGodson
doaj +1 more source
Endogenous inhibitory mechanisms in asthma
Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E2, prostaglandin I2 ...
Sergio E. Chiarella, MD +1 more
doaj +1 more source
Vagus nerve controls resolution and pro-resolving mediators of inflammation [PDF]
Resolution of inflammation is now recognized as a biosynthetically active process involving pro-resolving mediators. Here, we show in zymosan-initiated peritoneal inflammation that the vagus nerve regulates local expression of netrin-1, an axonal ...
Dalli, Jesmond +4 more
core +1 more source
Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA
PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in drug
Jannicke Irina Nesman +5 more
doaj +1 more source
Neutrophil unsaturated fatty acid release by GM-CSF is impaired in cystic fibrosis [PDF]
Dysregulated inflammation in cystic fibrosis (CF) is attributed to an altered production of inflammatory mediators derived from polyunsaturated lipids.
Elena Bravo +3 more
core +2 more sources
Resolution of inflammation is an active process involving specialized proresolving mediators (SPM) formed from the n-3 fatty acids. This study examined the effect of n-3 fatty acid supplementation and aspirin on plasma SPMs in healthy humans.
Anne Barden +4 more
doaj +1 more source
Assessing the diversity of the virulence potential of Escherichia coli isolated from bacteremia in São Paulo, Brazil [PDF]
Most of the knowledge of the virulence determinants of extraintestinal pathogenic Escherichia coli (ExPEC) comes from studies with human strains causing urinary tract infections and neonatal meningitis and animal strains causing avian colibacillosis.
Pignatari, Antonio Carlos Campos +3 more
core +1 more source
Protectin and resolvin gut inflammation [PDF]
Inflammation Even when laced with syrup, cod-liver oil is disgusting, but it is an important source of omega-3-docosapentaenoic fatty acid (DPA). After being swallowed, DPA is converted into specialized proresolving lipid mediators (SPMs), including protectin and resolvin.
openaire +2 more sources
Resolvins and protectins: mediating solutions to inflammation [PDF]
Resolution of inflammation has historically been viewed as a passive process, occurring as a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as leukotrienes and prostaglandins. Thus, most anti‐inflammatory drugs have traditionally targeted primarily mediator pathways that are engaged at the onset of inflammation ...
Payal, Kohli, Bruce D, Levy
openaire +2 more sources
Most polyunsaturated fatty acids have the minimal 1,4-cis,cis-pentadiene configuration to be oxygenated into a conjugated diene hydroperoxide. This product is usually reduced into the corresponding hydroxy derivative by cell glutathione peroxidases.
Lagarde Michel
doaj +1 more source

