Results 131 to 140 of about 4,792 (191)

Mechanisms and Clinical Manifestations of Age‐Related Impairment in Wound Healing

International Wound Journal, Volume 23, Issue 7, July 2026.
ABSTRACT Chronic wounds account for a considerable burden on the overall US healthcare system, affecting an estimated 10.2 million people and costing as much as $148 billion dollars in 2022 alone. Elderly patients suffer disproportionately, as nearly 85% of the chronic wound population is over the age of 65 years old.
Daniel A. Rabin, Tiffany Kim, Julia K. Kaniuk, Marlynn P. Lopez, Spencer Green, Aneeq S. Chaudhry, Katherine Kozlowski, Diana Griffin, Tarifa H. Adam, Thomas A. Mustoe, Robert D. Galiano   +10 more
wiley   +1 more source

Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders

Frontiers in Endocrinology
Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic clinical condition characterized by pathological and physiological interactions among metabolic abnormalities, chronic kidney disease, and cardiovascular diseases, leading to multi-organ dysfunction and a higher incidence of cardiovascular endpoints.
Shihan Zhang, Shasha Tang, Yalei Liu, Binghua Xue, Qinyuan Xie, Lingyun Zhao, Huijuan Yuan   +6 more
openaire   +3 more sources

Loop diuretics in anuric hemodialysis patients for the clearance of protein-bound uremic toxins

Clinical Kidney Journal
ABSTRACT Background In chronic kidney disease, the accumulation of protein-bound uremic toxins (PBUTs), such as hippuric acid (HA), p-cresyl sulfate (PCS) and indoxyl sulfate (IS), contributes to systemic toxicity and organ dysfunction.
Didier Sánchez-Ospina, Maria Romero-Cote, Lucia Criado-Bellido, Maria Isabel Saez-Calero, Badawi Hijazi-Prieto, Sandra Delgado-Cuesta, Francisco Herrera-Gómez, Maddalen Mujika-Marticorena, Emilio Gonzalez-Parra, Maria Jesus Izquierdo-Ortiz, Sebastián Mas-Fontao   +10 more
openaire   +2 more sources

Lymphocyte Phenotypes and Protein-Bound Uremic Toxins as Determinants of Clinical Outcomes in Hemodialysis Patients

International Journal of Molecular Sciences
The impact of protein bound uremic toxins (PBUTs) and lymphocyte alterations in morbidity and mortality in patients on hemodialysis (HD) is of great concern. The aim of this study was the assessment of association between PBUTs, immunosenescent lymphocytes’ phenotype and clinical events [cardiovascular, severe infections (hospitalization due to ...
Theodoros Tourountzis, Georgios Lioulios, Stamatia Stai, Steven Van Laecke, Eleni Moysidou, Michalis Christodoulou, Ariadni Fouza, Asimina Fylaktou, Konstantia Kantartzi, Griet Glorieux, Maria Stangou   +10 more
openaire   +3 more sources

The Arrhythmogenic Effect of Protein-Bound Uremic Toxin p-Cresylsulfate: An In Vitro Study. [PDF]

Acta Cardiol Sin, 2019
Tsai IT, Hsu CC, Hung WC, Wang CP, Yu TH, Houng JY, Lee KT, Tang WH.   +7 more
europepmc   +1 more source

Unambiguous Characterization of p-Cresyl Sulfate, a Protein-Bound Uremic Toxin, as Biomarker of Heart and Kidney Disease. [PDF]

Molecules, 2019
Paroni R, Casati S, Dei Cas M, Bignotto M, Rubino FM, Ciuffreda P.   +5 more
europepmc   +1 more source

In silico comparison of protein-bound uremic toxin removal by hemodialysis, hemodiafiltration, membrane adsorption, and binding competition. [PDF]

Sci Rep, 2019
Maheshwari V, Thijssen S, Tao X, Fuertinger DH, Kappel F, Kotanko P.   +5 more
europepmc   +1 more source

The impact of antihypertensive pharmacotherapy on interplay between protein-bound uremic toxin (indoxyl sulfate) and markers of inflammation in patients with chronic kidney disease. [PDF]

Int Urol Nephrol, 2019
Kaminski TW, Pawlak K, Karbowska M, Znorko B, Mor AL, Mysliwiec M, Pawlak D.   +6 more
europepmc   +1 more source

FP464COMPARISON OF EXTRACORPOREAL THERAPIES FOR PROTEIN-BOUND UREMIC TOXINS REMOVAL [PDF]

Nephrology Dialysis Transplantation, 2018
Vaibhav Maheshwari, Stephan Thijssen, Xia Tao, Doris Fuertinger, Franz Kappel, Peter Kotanko   +5 more
openaire   +1 more source

Precision Hemodialysis Using Sorbents to Remove Protein-Bound Uremic Toxins

Kidney360, 2023
openaire   +2 more sources