Results 131 to 140 of about 1,466,359 (163)

Protein homeostasis in chronic hemodialysis patients

Current Opinion in Clinical Nutrition and Metabolic Care, 2004
Nutritional status is an important predictor of clinical outcome in chronic hemodialysis patients, as uremic malnutrition is strongly associated with an increased risk of death and hospitalization events. Decreased muscle mass is the most significant predictor of morbidity and mortality in these patients.
Lara B, Pupim, Paul J, Flakoll, T Alp, Ikizler   +2 more
openaire   +2 more sources

Proteins of Iron Homeostasis

2011
Iron is essential for a number of biochemical functions in the body including the transport of oxygen in the blood and energy production in the mitochondria. Therefore, humans require an abundant and regular source of dietary iron to maintain normal health.
Surjit Kaila Srai, Paul Sharp
openaire   +1 more source

Protein homeostasis limiting cancer

Science Signaling, 2016
A protein involved in protein homeostasis limits the maturation of IGF1R and the overproduction of blood cells.
openaire   +1 more source

Presynaptic protein homeostasis and neuronal function

Current Opinion in Genetics & Development, 2017
Proteome integrity is maintained by a coordinated network of molecular chaperones, by protein degradation machineries and by their regulators. Numerous human pathologies are considered as diseases of compromised protein homeostasis (proteostasis), including neurodegeneration.
Wang, Yu-Chun, Lauwers, Elsa, Verstreken, Patrik   +2 more
openaire   +2 more sources

Protein Homeostasis

2021
openaire   +1 more source

Mechanisms, regulation and functions of the unfolded protein response

Nature Reviews Molecular Cell Biology, 2020
Claudio Hetz, Kezhong Zhang, Randal J Kaufman   +2 more
exaly  

Zinc Homeostasis Ensures Protein Homeostasis in the Early Secretory Pathway

Zinc is an essential trace element involved in numerous biological processes. More than 10% of the human proteome binds zinc ions (Zn2+), and much attention has been paid to the roles of Zn2+ in regulating protein structure and function. In this chapter, we summarize how zinc transporters contribute to the maintenance of zinc homeostasis in the early ...
Yuta Amagai, Kenji Inaba
openaire   +1 more source

Protein Homeostasis Diseases

2020
openaire   +1 more source

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

Nature Reviews Molecular Cell Biology, 2021
Simon Alberti, Anthony A Hyman
exaly  

The mechanisms of integral membrane protein biogenesis

Nature Reviews Molecular Cell Biology, 2021
Ramanujan Shankar Hegde, Robert J Keenan
exaly