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2011
Iron is essential for a number of biochemical functions in the body including the transport of oxygen in the blood and energy production in the mitochondria. Therefore, humans require an abundant and regular source of dietary iron to maintain normal health.
Surjit Kaila Srai, Paul Sharp
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Iron is essential for a number of biochemical functions in the body including the transport of oxygen in the blood and energy production in the mitochondria. Therefore, humans require an abundant and regular source of dietary iron to maintain normal health.
Surjit Kaila Srai, Paul Sharp
openaire +1 more source
Protein homeostasis in chronic hemodialysis patients
Current Opinion in Clinical Nutrition and Metabolic Care, 2004Nutritional status is an important predictor of clinical outcome in chronic hemodialysis patients, as uremic malnutrition is strongly associated with an increased risk of death and hospitalization events. Decreased muscle mass is the most significant predictor of morbidity and mortality in these patients.
Lara B, Pupim +2 more
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Sarcopenia: Tilting the Balance of Protein Homeostasis
PROTEOMICS, 2019AbstractSarcopenia, defined as age‐associated decline of muscle mass and function, is a risk factor for mortality and disability, and comorbid with several chronic diseases such as type II diabetes and cardiovascular diseases. Clinical trials showed that nutritional supplements had positive effects on muscle mass, but not on muscle function and ...
Kuan Ting Tan +2 more
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Nutrition and protein energy homeostasis in elderly
Mechanisms of Ageing and Development, 2014Protein-energy homeostasis is a major determinant of healthy aging. Inadequate nutritional intakes and physical activity, together with endocrine disturbances are associated with of sarcopenia and frailty. Guidelines from scientific societies mainly address the quantitative aspects of protein and energy nutrition in elderly.
Boirie, Y. +3 more
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DNA damage and regulation of protein homeostasis
DNA Repair, 2021The accumulation of unrepaired DNA lesions is associated with many pathological outcomes in humans, particularly in neurodegenerative diseases and in normal aging. Evidence supporting a causal role for DNA damage in the onset and progression of neurodegenerative disease has come from rare human patients with mutations in DNA damage response genes as ...
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Breathing for protein function and [H+] homeostasis
Respiration Physiology, 1993Based on a physicochemical analysis of H+ homeostasis, we hypothesize that PCO2 and strong ions, and not [H+], act independently on chemosensors in the central nervous system to regulate ventilation. [H+] in body fluids and the pK of histidine imidazole groups of proteins must be regulated in relation to each other to preserve protein conformation and ...
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The tumour-promoting role of protein homeostasis: Implications for cancer immunotherapy
Cancer Letters, 2023Huabing Tan +2 more
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Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?
Open Biology, 2021Anna Ainslie +2 more
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