Results 251 to 260 of about 5,116,336 (302)

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system. [PDF]

iScience
Mendez-Lopez M, Besse A, Zuppinger C, Perez-Shibayama C, Gil-Cruz C, Florea BI, De Martin A, Lütge M, Beckerova D, Klimovic S, Zhou X, Rasche L, Pribyl J, Rotrekl V, Ludewig B, Overkleeft HS, Besse L, Driessen C.   +17 more
europepmc   +1 more source

Collagen‐Based Gut‐on‐Chip for In Vitro Modeling of Intestinal Barrier Function and Host‐Pathogen Interactions

Advanced Materials Technologies, EarlyView.
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García, Jacques Leng, Hugo de Oliveira, Pierre Nassoy, Karine Dementhon   +4 more
wiley   +1 more source

Author Correction: A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis. [PDF]

Nat Commun
Shen J, Zhao Q, Wang X, Gao C, Zhu Y, Zeng Y, Jiang L.   +6 more
europepmc   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

α-Asarone Maintains Protein Homeostasis Through SKN-1-Mediated Proteasome and Autophagy Pathways to Mitigate Aβ-Associated Toxicity in <i>Caenorhabditis elegans</i>. [PDF]

Antioxidants (Basel)
Wei C, Chen X, Sun M, Cao J, Liao D, Cheng Z, Wang H.   +6 more
europepmc   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

The novel amino-artemisinin derivative WHN-11 disrupts mitochondria and protein homeostasis, and induces autophagy and apoptosis in cancer cells. [PDF]

Sci Rep
Kajewole D, Wong HN, von Kriegsheim A, Haynes RK, de la Mare JA, Edkins AL.   +5 more
europepmc   +1 more source

SUMO-targeted Ubiquitin Ligases as crucial mediators of protein homeostasis in Candida glabrata. [PDF]

PLoS Pathog
Gupta D, Shukla R, Mishra K.
europepmc   +1 more source