Results 81 to 90 of about 4,093 (168)

Analysis of genetic mutations using a recombinant model of the mammalian pyruvate dehydrogenase complex [PDF]

, 2008
The human mitochondrial pyruvate dehydrogenase complex (PDC) is a vital metabolic assembly that controls the key committed step in aerobic carbohydrate utilisation and energy production and as such is responsible for overall glucose homeostasis in man ...
Singh, Geetanjali
core   +1 more source

Quantitative study of H protein lipoylation of the glycine cleavage system and a strategy to increase its activity by co-expression of LplA. [PDF]

J Biol Eng, 2019
Zhang X, Li M, Xu Y, Ren J, Zeng AP.
europepmc   +1 more source

Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis. [PDF]

Nat Commun
Hsiao JC, Warui DM, Kwon JJ, Dreishpoon MB, Bick NR, Blue-Lahom T, Root DE, Booker SJ, Tsvetkov P.   +8 more
europepmc   +1 more source

Targeting multiple genetic defects of mitochondrial diseases with a single bacterial lipoate protein ligase. [PDF]

Sci Adv
Hu Z, Yu J, Liu Z, Jiang M, Zeng AP.
europepmc   +1 more source

Ferredoxins: master regulators in mitochondrial redox homeostasis and programmed cell death. [PDF]

Redox Biol
Lu Y, Wu Y, Yang C, Zhou Y, Ren X, Li H, Huang H, Pan F, Deng A, Lu Y, Yang J, Tong X, Li Y, Du J.   +13 more
europepmc   +1 more source

Role of Ferredoxin 1 <i>(FDX1)</i> in cancer and its therapeutic potential. [PDF]

Cancer Pathog Ther
He F, Zhao H, Gao R, Lu M, Wang S, Chen Y, Peng L, Xia J.   +7 more
europepmc   +1 more source

A mouse model of MEPAN demonstrates a role for mitochondrial fatty acid synthesis in iron-sulfur cluster and supercomplex formation. [PDF]

Proc Natl Acad Sci U S A
Murdock DG, Janssen KA, Keller K, Mitchell KL, Beauplan M, O'Brien WT, D'Alessandro L, Haltom JA, Wallace DC.   +8 more
europepmc   +1 more source

Copper Dyshomeostasis, Redox Buffering and Immune Aging Converge on Cuproptosis in Age-Related Diseases. [PDF]

Antioxidants (Basel)
Jin Y, Lu K, Yang Y.
europepmc   +1 more source

The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism [PDF]

, 2018
Dange, Thomas, Hallett, Joshua P., Jubinsky, Paul T., Moir, Robyn, Schmidt, Marion, Short, Mary K., Tar, Krisztina, Willis, Ian M.   +7 more
core   +1 more source

NEDD4L induces mitochondrial dysfunction and neurodegeneration by promoting LIPT2 degradation in Huntington's disease. [PDF]

Proc Natl Acad Sci U S A
Fan P, Liu Y, Liu C, Yao H, Xu S, Jiang Y, Wu Y, Liu Y, Guo X.   +8 more
europepmc   +1 more source