Results 11 to 20 of about 750,523 (310)

Coordination of RNA Processing Regulation by Signal Transduction Pathways

open access: yesBiomolecules, 2021
Signal transduction pathways transmit the information received from external and internal cues and generate a response that allows the cell to adapt to changes in the surrounding environment.
Veronica Ruta   +2 more
doaj   +1 more source

Molecular Dynamics Study of Citrullinated Proteins Associated with the Development of Rheumatoid Arthritis

open access: yesProteomes, 2022
Biological activity regulation by protein post-translational modification (PTM) is critical for cell function, development, differentiation, and survival.
Amir Taldaev   +6 more
doaj   +1 more source

Analyzing and Comparing Omicron Lineage Variants Protein-Protein Interaction Network using Centrality Measure [PDF]

open access: yesSN Computer Science.4(2023)299, 2023
The Worldwide spread of the Omicron lineage variants has now been confirmed. It is crucial to understand the process of cellular life and to discover new drugs need to identify the important proteins in a protein interaction network (PPIN). PPINs are often represented by graphs in bioinformatics, which describe cell processes.
arxiv   +1 more source

A Comprehensive Analysis of the Role of hnRNP A1 Function and Dysfunction in the Pathogenesis of Neurodegenerative Disease

open access: yesFrontiers in Molecular Biosciences, 2021
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP family of conserved proteins that is involved in RNA transcription, pre-mRNA splicing, mRNA transport, protein translation, microRNA processing, telomere maintenance and the ...
Joseph P. Clarke   +9 more
doaj   +1 more source

Extensive post‐translational processing of potato tuber storage proteins and vacuolar targeting [PDF]

open access: yesThe FEBS Journal, 2011
Potato tuber storage proteins were obtained from vacuoles isolated from field‐grown starch potato tubers cv. Kuras. Vacuole sap proteins fractionated by gel filtration were studied by mass spectrometric analyses of trypsin and chymotrypsin digestions. The tuber vacuole appears to be a typical protein storage vacuole absent of proteolytic and glycolytic
Jørgensen, Malene   +2 more
openaire   +5 more sources

Post-Translational Modifications of ATG4B in the Regulation of Autophagy

open access: yesCells, 2022
Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
doaj   +1 more source

Processing and targeting of proteins derived from polyprotein with 2A and LP4/2A as peptide linkers in a maize expression system. [PDF]

open access: yesPLoS ONE, 2017
In the transformation of multiple genes, gene fusion is an attractive alternative to other methods, including sexual crossing, re-transformation, and co-transformation, among others.
He Sun   +4 more
doaj   +1 more source

Proteomic and molecular dynamic investigations of PTM-induced structural fluctuations in breast and ovarian cancer

open access: yesScientific Reports, 2021
Post-translational processing leads to conformational changes in protein structure that modulate molecular functions and change the signature of metabolic transformations and immune responses.
Dmitry Tikhonov   +11 more
doaj   +1 more source

Cytoplasmic interaction with CYCLE promotes the post‐translational processing of the circadian CLOCK protein [PDF]

open access: yesFEBS Letters, 2009
CLK (uniprotkb:O61735) binds (MI:0407) to Cyc (uniprotkb:O61734) by pull down (MI:0096)
Christian Maurer   +2 more
openaire   +3 more sources

Large-scale protein-protein post-translational modification extraction with distant supervision and confidence calibrated BioBERT

open access: yesBMC Bioinformatics, 2022
Motivation Protein-protein interactions (PPIs) are critical to normal cellular function and are related to many disease pathways. A range of protein functions are mediated and regulated by protein interactions through post-translational modifications ...
Aparna Elangovan   +4 more
doaj   +1 more source

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