Extensive post‐translational processing of potato tuber storage proteins and vacuolar targeting [PDF]
The FEBS Journal, 2011 Potato tuber storage proteins were obtained from vacuoles isolated from field‐grown starch potato tubers cv. Kuras. Vacuole sap proteins fractionated by gel filtration were studied by mass spectrometric analyses of trypsin and chymotrypsin digestions. The tuber vacuole appears to be a typical protein storage vacuole absent of proteolytic and glycolytic
Jørgensen, Malene +2 more
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Post-Translational Modifications of ATG4B in the Regulation of Autophagy
Cells, 2022 Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
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SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors. [PDF]
PLoS ONE, 2010 BACKGROUND:Hedgehog (Hh) signaling, a vital signaling pathway for the development and homeostasis of vertebrate tissues, is mediated by members of the Gli family of zinc finger transcription factors. Hh signaling increases the transcriptional activity of
Barny Cox, James Briscoe, Fausto Ulloa
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Processing and targeting of proteins derived from polyprotein with 2A and LP4/2A as peptide linkers in a maize expression system. [PDF]
PLoS ONE, 2017 In the transformation of multiple genes, gene fusion is an attractive alternative to other methods, including sexual crossing, re-transformation, and co-transformation, among others.
He Sun +4 more
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Scientific Reports, 2021 Post-translational processing leads to conformational changes in protein structure that modulate molecular functions and change the signature of metabolic transformations and immune responses.
Dmitry Tikhonov +11 more
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Cytoplasmic interaction with CYCLE promotes the post‐translational processing of the circadian CLOCK protein [PDF]
FEBS Letters, 2009 CLK (uniprotkb:O61735) binds (MI:0407) to Cyc (uniprotkb:O61734) by pull down (MI:0096)
Christian Maurer +2 more
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Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]
, 2013 It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin +6 more
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BMC Bioinformatics, 2022 Motivation Protein-protein interactions (PPIs) are critical to normal cellular function and are related to many disease pathways. A range of protein functions are mediated and regulated by protein interactions through post-translational modifications ...
Aparna Elangovan +4 more
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Circadian rhythms and post-transcriptional regulation in higher plants [PDF]
, 2015 The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Romanowski, Andrés +1 more
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Localization and Post-translational Processing of the Wound-induced Leucine Aminopeptidase Proteins of Tomato [PDF]
Journal of Biological Chemistry, 1996 Leucine aminopeptidase (LAP) is induced by wounding and bacterial pathogen infection in tomato. DNA blot analysis of XbaI-digested lambdalap genomic clones demonstrated that LapA1 and LapA2 cDNAs were encoded by two different LapA genes in the tomato genome. The coding and untranslated regions of LapA1 and LapA2 mRNAs shared more than 93% identity. The
Yong-Qiang Gu +2 more
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