Results 51 to 60 of about 508,657 (349)
Journal of Biological Chemistry, 1986 Glucagon is a pancreatic hormone of 29 amino acids that regulates carbohydrate metabolism and glicentin is an intestinal peptide of 69 amino acids that contains the sequence of glucagon flanked by peptide extensions at the amino and carboxy termini.
S. Mojsov +5 more
semanticscholar +1 more source
Automated assembly of molecular mechanisms at scale from text mining and curated databases
Molecular Systems Biology, 2023 The analysis of omic data depends on machine‐readable information about protein interactions, modifications, and activities as found in protein interaction networks, databases of post‐translational modifications, and curated models of gene and protein ...
John A Bachman +2 more
doaj +1 more source
Targeting GLI factors to inhibit the Hedgehog pathway [PDF]
, 2015 Hedgehog (Hh) signaling has emerged in recent years as an attractive target for anticancer therapy because its aberrant activation is implicated in several cancers. Major progress has been made in the development of SMOOTHENED (SMO) antagonists, although
Alfonsi, Romina +4 more
core +2 more sources
Journal of Biological Chemistry, 2001 We examined the biosynthesis and post-translational processing of the brain-derived neurotrophic factor precursor (pro-BDNF) in cells infected with a pro-BDNF-encoding vaccinia virus.
S. Mowla +6 more
semanticscholar +1 more source
Journal of Biological Chemistry, 2009 The regulation of lipid homeostasis by insulin is mediated in part by the enhanced transcription of the gene encoding SREBP-1c (sterol regulatory element-binding protein-1c).
C. Yellaturu +8 more
semanticscholar +1 more source
New mechanism for post-translational processing during assembly of a cytoplasmic membrane protein? [PDF]
Journal of Bacteriology, 1981 Insertion of nitrate reductase into the Escherichia coli cytoplasmic membrane was examined by following the fate of pulse-labeled enzyme in both the membrane and cytoplasm during various times after the addition of an unlabeled chase. The polypeptide composition of this labeled enzyme was determined by autoradiography of immunoprecipitated material ...
C H, MacGregor, G E, McElhaney
openaire +2 more sources
NEURONIC SYSTEM INSIDE NEURONS: MOLECULAR BIOLOGY AND BIOPHYSICS OF NEURONAL MICROTUBULES [PDF]
, 2004 Neurons are highly specialized cells that input, process, store and output information. Interneuronal communication is achieved in four basic ways: (i) Ca2+ evoked exocytosis with chemical neurotransmission, (ii) gap junction electrotonic coupling, (iii)
Georgiev, Danko +2 more
core +1 more source
Poly ADP-ribosylation of proteins. Processivity of a post-translational modification.
The Journal of biological chemistry, 1989 The nuclear enzyme poly(ADP-ribose) polymerase (EC 2.4.2.30) participates in DNA excision repair by post-translational selfmodification ("automodification") and the modification of other chromatin proteins ("heteromodification") with ADP-ribose polymers.
H, Naegeli, P, Loetscher, F R, Althaus
openaire +2 more sources
Cell Communication and Signaling, 2021 Controlling the activation of the NLRP3 inflammasome by post-translational modifications (PTMs) of critical protein subunits has emerged as a key determinant in inflammatory processes as well as in pathophysiology. In this review, we put into context the
Zhu Liang +3 more
doaj +1 more source
Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery. [PDF]
, 2018 The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via the dopamine (DA) receptor D2 (DRD2).
Blondell, Lucy +8 more
core +4 more sources