Results 61 to 70 of about 3,931,468 (303)

Protein import into chloroplasts: new aspects of a well-known topic [PDF]

, 2007
Protein import into plant chloroplasts is a fascinating topic that is being investigated by many research groups. Since the majority of chloroplast proteins are synthesised as precursor proteins in the cytosol, they have to be posttranslationally ...
Bölter, Bettina, Stengel, Anna, Soil, Juergen   +2 more
core   +1 more source

Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery

Toxins, 2014
To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings,
Philip A. Gurnev, Ekaterina M. Nestorovich   +1 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Environmental salinity determines the specificity and need for tat-dependent secretion of the YwbN protein in bacillus subtilis [PDF]

, 2011
Twin-arginine protein translocation (Tat) pathways are required for transport of folded proteins across bacterial, archaeal and chloroplast membranes. Recent studies indicate that Tat has evolved into a mainstream pathway for protein secretion in certain
Miethke, Marcus, Theresa Winter, Schaffer Marc, van der Ploeg, René, Jan Maarten van Dijl, Harwood, Colin R., Denham, Emma, Monteferrante, Carmine G., Ulrike Mäder, Marcus Miethke, Maeder, Ulrike, van der Ploeg René, René van der Ploeg, Mohamed A Marahiel, Denham, Emma L., Harwood Colin R., Colin R. Harwood, van Dijl, Jan Maarten, Homuth, Georg, Hecker Michael, Monteferrante Carmine G., Carmine G Monteferrante, Georg Homuth, Mäder Ulrike, Mäder, Ulrike, van Dijl Jan Maarten, Winter Theresa, Emma L. Denham, Homuth Georg, Miethke Marcus, Schaffer, Marc, Michael Hecker, Marahiel Mohamed A., Hecker, Michael, Dijl, Jan Maarten van, Winter, Theresa, Haike Antelmann, Marahiel, Mohamed A., Antelmann, Haike, Antelmann Haike, Carmine G. Monteferrante, Emma L Denham, Denham Emma L., Colin R Harwood, Marc Schaffer, Mohamed A. Marahiel   +45 more
core   +2 more sources

PRAT Proteins Operate in Organellar Protein Import and Export in Arabidopsis thaliana

Plants, 2021
Chloroplasts need to import preproteins and amino acids from the cytosol during their light-induced differentiation. Similarly, chloroplasts have to export organic matter including proteins and amino acids during leaf senescence.
Claudia Rossig, John Gray, Oscar Valdes, Armin Springer, Sachin Rustgi, Diter von Wettstein, Christiane Reinbothe, Joachim Rassow, Steffen Reinbothe   +8 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structure of a translocation signal domain mediating conjugative transfer by Type IV secretion systems [PDF]

, 2013
Relaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from one bacterium to another during conjugation. They covalently react with a specific phosphodiester bond within DNA origin of transfer sequences, forming a nucleo ...
Redzej, Adam, Topf, Maya, Zechner, E.L., Lang, S., Waksman, Gabriel, Zangger, K., Gruber, C.J., Ilangovan, Aravindan   +7 more
core   +1 more source

Novel Technology for Protein-Protein Interaction-based Targeted Drug Discovery

Journal of Analytical Science and Technology, 2011
We have developed a simple but highly efficient in-cell protein-protein interaction (PPI) discovery system based on the translocation properties of protein kinase C- and its C1a domain in live cells.
Jung Me Hwang, Kyung-Bok Lee, Jong-Soon Choi, Jaerang Rho, Gun-Hwa Kim, Seung Il Kim, Soohyun Kim, Zee-Won Lee   +7 more
doaj  

Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting

Cells, 2022
Importing proteins into the endoplasmic reticulum (ER) is essential for about 30% of the human proteome. It involves the targeting of precursor proteins to the ER and their insertion into or translocation across the ER membrane. Furthermore, it relies on
Andrea Tirincsi, Sarah O’Keefe, Duy Nguyen, Mark Sicking, Johanna Dudek, Friedrich Förster, Martin Jung, Drazena Hadzibeganovic, Volkhard Helms, Stephen High, Richard Zimmermann, Sven Lang   +11 more
doaj   +1 more source

Protein translocation across membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2001
Cellular membranes act as semipermeable barriers to ions and macromolecules. Specialized mechanisms of transport of proteins across membranes have been developed during evolution. There are common mechanistic themes among protein translocation systems in bacteria and in eukaryotic cells.
Agarraberes, Fernando A, Dice, J.Fred
openaire   +2 more sources