Results 81 to 90 of about 18,213,481 (205)

The aspartic proteinase family of three Phytophthora species [PDF]

, 2011
Background - Phytophthora species are oomycete plant pathogens with such major social and economic impact that genome sequences have been determined for Phytophthora infestans, P. sojae and P. ramorum.
Meijer, H.J.G., Have, A., ten, Kay, J., Kan, J.A.L., van   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Case for diagnosis. Cutaneous small vessel vasculitis (anti-proteinase 3 positive), fever, hemoptysis, and lung cavitation in an adult, [PDF]

Anais Brasileiros de Dermatologia
Small vessel vasculitis with anti-proteinase antibodies 3 is an atypical clinical presentation of tuberculosis. The authors present the case of a 47-year-old male patient, with palpable purpura and palmoplantar hemorrhagic blisters, with subsequent ...
Luana Moraes Campos, Mariana Righetto de Ré, Priscila Neri Lacerda, Hélio Amante Miot   +3 more
doaj   +2 more sources

Biofilm Formation and Aspartyl Proteinase Activity and Their Association with Azole Resistance Among Candida albicans Causing Vulvovaginal Candidiasis, Egypt

, 2023
Marian A Gerges,1 Yasmin Ahmed Fahmy,1 Thoraya Hosny,2 Nessma H Gandor,2 Sherif Y Mohammed,2 Tahia Mohamed Ahmed Mohamed,2 Nabila Elsayed Mousa Abdelmoteleb,3 Noura E Esmaeel1 1Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig ...
Fahmy YA, Gandor NH, Hosny T, Mohammed SY, Mohamed TMA, Gerges MA, Abdelmoteleb NEM, Esmaeel NE   +7 more
core  

Proteinase 3 gene polymorphisms and Wegener's granulomatosis [PDF]

, 2000
Proteinase 3 gene polymorphisms and Wegener's granulomatosis.BackgroundWegener's granulomatosis (WG) is a rare systemic autoimmune disease characterized by small-vessel vasculitis leading to organ damage and the presence of antineutrophil cytoplasmic ...
Borgmann, Stefan, Gencik, Martin, Fricke, Harald, Meller, Stephan   +3 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis

Frontiers in Immunology
ObjectiveDespite recent advances, the pathophysiological mechanisms underlying anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) remain incompletely understood, and comparative proteomic analyses of AAV subtypes are lacking.
Erik Hellbacher, Erik Hellbacher, Vincent van Hoef, Alina Johansson, Ann Knight, Ann Knight, Iva Gunnarsson, Iva Gunnarsson, Annette Bruchfeld, Annette Bruchfeld, Per Eriksson, Sophie Ohlsson, Solbritt Rantapää-Dahlqvist, Johanna Dahlqvist, Johanna Dahlqvist   +14 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical utility of proteinase 3-antineutrophil cytoplasmic antibody at diagnosis in predicting subsequent relapse in patients with microscopic polyangiitis

Frontiers in Medicine
BackgroundIn real clinical practice, patients classified as microscopic polyangiitis (MPA) according to the new 2022 criteria, despite proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA) positivity, are occasionally encountered.
Jang Woo Ha, Oh Chan Kwon, Yong-Beom Park, Yong-Beom Park, Sang-Won Lee, Sang-Won Lee   +5 more
doaj   +1 more source