Results 11 to 20 of about 110,290 (187)
Cells, 2021 Small leucine-rich proteoglycans (SLRPs) regulate different processes and undergo significant alterations in various diseases. Colon carcinomas (CCs) are heterogeneous pathologies with important clinical and molecular differences depending on their ...
Maria Pilar Solis-Hernandez +9 more
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Interplay between Cell-Surface Receptors and Extracellular Matrix in Skin
Biomolecules, 2020 Skin consists of the epidermis and dermis, which are connected by a specialized basement membrane—the epidermal basement membrane. Both the epidermal basement membrane and the underlying interstitial extracellular matrix (ECM) created by dermal ...
Svenja Kleiser, Alexander Nyström
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Frontiers in Oncology, 2022 Extracellular and cell surface chondroitin sulfates (CSs) regulate cancer cell properties, including proliferation and invasion. Thus, it is necessary to understand the mechanisms underlying their roles in cancer.
Satomi Nadanaka +2 more
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Syndecan receptors: pericellular regulators in development and inflammatory disease [PDF]
Open Biology, 2021 The syndecans are the major family of transmembrane proteoglycans, usually bearing multiple heparan sulfate chains. They are present on virtually all nucleated cells of vertebrates and are also present in invertebrates, indicative of a long evolutionary ...
Sandeep Gopal +4 more
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Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts
Biomolecules, 2020 Fibrosis is a fundamental feature of systemic sclerosis (SSc) and is characterized by excessive accumulation of extracellular matrix components like proteoglycans (PG) or collagens in skin and internal organs.
Thanh-Diep Ly +7 more
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Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated.
Toshihiro Tsuruda +12 more
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Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
Matrix Biology, 2015 We provide a comprehensive classification of the proteoglycan gene families and respective protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular location, overall gene/protein homology, and the utilization of ...
R. Iozzo, L. Schaefer
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Journal of Lipid Research, 2001 Endogenous expression of apolipoprotein (apo)E in macrophages facilitates cholesterol efflux in the presence and absence of extracellular sterol acceptors. A proteoglycan-associated pool of apoE has also been described.
Chen-Yi Lin +2 more
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Frontiers in Immunology, 2020 The attachment of a variety of Lactobacilli to the mucosal surfaces is accomplished through the interaction of OppA, a superficial bacterial protein also involved in oligopeptide internalization, and the glycosaminoglycan moiety of the proteoglycans that
Carla Martín +9 more
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Frontiers in Oncology, 2014 Heparan sulfates (HS) are key components of mammalian cells surface and extracellular matrix. Structure and composition of HS, generated by HS biosynthetic system through non-template driven process, are significantly altered in cancer tissues.
Anastasia V Suhovskih +8 more
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