Results 21 to 30 of about 132,694 (329)

Adherence of Lactobacillus salivarius to HeLa Cells Promotes Changes in the Expression of the Genes Involved in Biosynthesis of Their Ligands

Frontiers in Immunology, 2020
The attachment of a variety of Lactobacilli to the mucosal surfaces is accomplished through the interaction of OppA, a superficial bacterial protein also involved in oligopeptide internalization, and the glycosaminoglycan moiety of the proteoglycans that
Carla Martín, Carla Martín, Carla Martín, Iván Fernández-Vega, Iván Fernández-Vega, Iván Fernández-Vega, Juan E. Suárez, Luis M. Quirós, Luis M. Quirós, Luis M. Quirós   +9 more
doaj   +1 more source

Smad4 regulates growth plate matrix production and chondrocyte polarity. [PDF]

, 2017
Smad4 is an intracellular effector of the TGFβ family that has been implicated in Myhre syndrome, a skeletal dysplasia characterized by short stature, brachydactyly and stiff joints.
Alliston, Tamara, Berthet, Ellora, Cantu, Andrea, Laird, Diana J, Whitaker, Amanda T   +4 more
core   +3 more sources

The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded

Cardiovascular Diabetology, 2005
The vascular endothelial basement membrane and extra cellular matrix is a compilation of different macromolecules organized by physical entanglements, opposing ionic charges, chemical covalent bonding, and cross-linking into a biomechanically active ...
Tyagi Suresh C, Sowers James R, Hayden Melvin R   +2 more
doaj   +1 more source

Chemotherapy-Induced Degradation of Glycosylated Components of the Brain Extracellular Matrix Promotes Glioblastoma Relapse Development in an Animal Model

Frontiers in Oncology, 2021
Adjuvant chemotherapy with temozolomide (TMZ) is an intrinsic part of glioblastoma multiforme (GBM) therapy targeted to eliminate residual GBM cells.
Alexandra Y. Tsidulko, Oleg B. Shevelev, Anna S. Khotskina, Mariia A. Kolpakova, Anastasia V. Suhovskih, Anastasia V. Suhovskih, Galina M. Kazanskaya, Alexander M. Volkov, Svetlana V. Aidagulova, Evgenii L. Zavyalov, Elvira V. Grigorieva, Elvira V. Grigorieva   +11 more
doaj   +1 more source

Metabolic response of human osteoarthritic cartilage to biochemically characterized collagen hydrolysates [PDF]

, 2017
The most frequent disease of the locomotor system is osteoarthritis (OA), which, as a chronic joint disease, might benefit more from nutrition than acute illnesses.
Gazova, Zuzana, Kordelle, Jens, Lochnit, Guenter, Schadow, Saskia, Siebert, Hans-Christian, Simons, Viktor S., Steinmeyer, Juergen   +6 more
core   +2 more sources

RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins [PDF]

, 2016
The sea urchin larval skeleton offers a simple model for formation of developmental patterns. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues expressed by the ectoderm.
Bardot, Evan, Blute, Todd A., Bradham, Cynthia A., Chaves, James, Chung, Oliver, Core, Amanda B., Coulombe-Huntington, Jasmin, Ferrell, Patrick, Fishman, Julie, Hameeduddin, Hajerah, Hewitt, Finnegan B., Hogan, John D., Ibn-Salem, Jonas, Keenan, Jessica L, Lee, David, Li, Christy, Luo, Lingqi, Oleinik, Ekaterina, Patel, Vijeta, Piacentino, Michael L., Poustka, Albert J., Ramachandran, Janani, Reyna, Arlene, Rose, Sviatlana, Speranza, Emily E., Yu, Jia, Zuch, Daniel T.   +26 more
core   +1 more source

Extracellular Matrix of Echinoderms

Marine Drugs, 2023
This review considers available data on the composition of the extracellular matrix (ECM) in echinoderms. The connective tissue in these animals has a rather complex organization.
Igor Yu. Dolmatov, Vladimir A. Nizhnichenko   +1 more
doaj   +1 more source

The Regulation of Aggrecanase ADAMTS-4 Expression in Human Achilles Tendon and tendon-Derived Cells [PDF]

, 2008
Several members of the ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) family have been identified as aggrecanases, whose substrates include versican, the principal large proteoglycan in the tendon extracellular matrix.
Corps, Anthony N., Curry, Valerie A., Harrall, Rebecca L., Hazleman, Brian L., Jones, Gavin C., Riley, Graham P.   +5 more
core   +2 more sources

The Effect of Intense Exercise on Equine Serum Proteoglycan-4/Lubricin

Frontiers in Veterinary Science, 2020
Objective: Local biological and biomechanical-stimuli modulate proteoglycan-4 secretion within synovial joints. For the horse, changes to proteoglycan-4 concentration and function are notable in acute joint injury and osteoarthritis. Proteoglycan-4 (also
Austyn Matheson, Suresh C. Regmi, Gregory D. Jay, Tannin A. Schmidt, W. Michael Scott, W. Michael Scott   +5 more
doaj   +1 more source

Transcriptional activity of heparan sulfate biosynthetic machinery is specifically impaired in benign prostate hyperplasia and prostate cancer

Frontiers in Oncology, 2014
Heparan sulfates (HS) are key components of mammalian cells surface and extracellular matrix. Structure and composition of HS, generated by HS biosynthetic system through non-template driven process, are significantly altered in cancer tissues.
Anastasia V Suhovskih, Anastasia V Suhovskih, Aneksandra Y Tsidulko, Olesya S Kutsenko, Anna V Kovner, Svetlana V Aidagulova, Ingemar eErnberg, Elvira V Grigorieva, Elvira V Grigorieva   +8 more
doaj   +1 more source