Results 31 to 40 of about 110,290 (187)

Mutable Collagenous Tissue: A Concept Generator for Biomimetic Materials and Devices

open access: yesMarine Drugs
Echinoderms (starfish, sea-urchins and their close relations) possess a unique type of collagenous tissue that is innervated by the motor nervous system and whose mechanical properties, such as tensile strength and elastic stiffness, can be altered in a ...
M. Daniela Candia Carnevali   +3 more
doaj   +1 more source

Endocan - a potential diagnostic marker for early onset sepsis in neonates

open access: yesJournal of Infection in Developing Countries, 2019
Introduction: Neonatal early onset sepsis assessment is based on the history of pregnancy and delivery and nonspecific clinical signs. None of the biomarkers currently in use for clinical practice has adequate prognostic value, so it is not possible to ...
Gabriela Ildiko Zonda   +5 more
doaj   +1 more source

The Role of Decorin and Biglycan Signaling in Tumorigenesis

open access: yesFrontiers in Oncology, 2021
The complex and adaptive nature of malignant neoplasm constitute a major challenge for the development of effective anti-oncogenic therapies. Emerging evidence has uncovered the pivotal functions exerted by the small leucine-rich proteoglycans, decorin ...
Valentina Diehl   +5 more
doaj   +1 more source

Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Siew Tein Wang, Boon Hoe Neo, Richard J Betts L’Oréal Research & Innovation, L’Oréal Singapore, SingaporeCorrespondence: Richard J Betts Email richard.betts@rd.loreal.comAbstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of ...
Wang ST, Neo BH, Betts RJ
doaj  

Regulation of Macrophage and Dendritic Cell Function by Chondroitin Sulfate in Innate to Antigen-Specific Adaptive Immunity

open access: yesFrontiers in Immunology, 2020
Chondroitin sulfate (CS), a type of glycosaminoglycan (GAG), is a linear acidic polysaccharide comprised of repeating disaccharides, modified with sulfate groups at various positions. Except for hyaluronan (HA), GAGs are covalently bound to core proteins,
Sonoko Hatano, Hideto Watanabe
doaj   +1 more source

Hair follicle proteoglycans

open access: yesJournal of Investigative Dermatology, 1993
Proteoglycans are polymorphic macromolecules present in all mammalian tissues, including the skin and its appendages. They consist of a core protein to which one or more glycosaminoglycan chains are covalently attached. Broadly, they can be divided into classes based on location and core protein structure.
openaire   +2 more sources

Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity

open access: yesProtein & Cell, 2017
The blood-brain barrier (BBB) is a tight boundary formed between endothelial cells and astrocytes, which separates and protects brain from most pathogens as well as neural toxins in circulation.
Bo Jing   +12 more
doaj   +1 more source

Tissue-specific expression of carbohydrate sulfotransferases drives keratan sulfate biosynthesis in the notochord and otic vesicles of Xenopus embryos

open access: yesFrontiers in Cell and Developmental Biology, 2023
Keratan sulfate (KS) is a glycosaminoglycan that is enriched in vertebrate cornea, cartilage, and brain. During embryonic development, highly sulfated KS (HSKS) is first detected in the developing notochord and then in otic vesicles; therefore, HSKS has ...
Yuuri Yasuoka, Yuuri Yasuoka
doaj   +1 more source

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

open access: yesNature, 1986
During inflammatory reactions, activated leukocytes are thought to produce a variety of small proteins (cytokines) that influence the behaviour of other cells (including other leukocytes).
J. Saklatvala
semanticscholar   +1 more source

A Reinterpretation of Evidence for the Endothelial Glycocalyx Filtration Structure

open access: yesFrontiers in Cell and Developmental Biology, 2021
The endothelial glycocalyx (eGlx) is thought to be the primary macromolecular filter for fluid flux out of the vasculature. This filter maintains the higher protein concentration within the vessel lumen relative to the tissue.
Kenton P. Arkill
doaj   +1 more source

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