Results 41 to 50 of about 110,290 (187)

Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species.

Journal of Biological Chemistry, 1989
The small proteoglycans (PG) of bone consist of two different molecular species: one containing one chondroitin sulfate chain (PG II) and the other, two chains (PG I). These two proteoglycans are found in many connective tissues and have Mr = 45,000 core
L. Fisher, J. Termine, M. Young
semanticscholar   +1 more source

Application of Proteoglycan from Oreochromis niloticus Cartilage in Silk fibroin/gelatin Scaffold for In vitro Wound Treatment

Journal of Health Science and Medical Research (JHSMR), 2015
Objective: To prepare silk fibroin/gelatin scaffold containing epidermal growth factor-like proteoglycan extracted from Oreochromis niloticus cartilage and characterize physical, chemical and biological properties of prepared scaffolds.
Panya Weerawatkapong, Pornanong Aramwit
doaj  

The Effects of Proteoglycan and Type II Collagen on T1ρ Relaxation Time of Articular Cartilage

대한영상의학회지, 2015
Purpose To evaluate the effects of proteoglycan and type II collagen within articular cartilage on T1ρ relaxation time of articular cartilage. Materials and Methods This study was exempted by the institutional and animal review boards, and informed ...
Won Seok Choi, Hye Jin Yoo, Sung Hwan Hong, Ja-Young Choi   +3 more
doaj   +1 more source

Neuroendocrine tumors show altered expression of chondroitin sulfate, glypican 1, glypican 5 and syndecan 2 depending on their differentiation grade

Frontiers in Oncology, 2014
Neuroendocrine tumors are found throughout the body and are important as they give rise to distinct clinical syndromes. Glycosaminoglycans, in proteoglycan form or as free chains, play vital roles in every step of tumor progression.
Olivia eGarcía-Suárez, Beatriz eGarcía, Iván eFernández-Vega, Aurora eAstudillo, Aurora eAstudillo, Luis M Quirós, Luis M Quirós   +6 more
doaj   +1 more source

The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury

Journal of Neuroinflammation, 2012
BackgroundChondroitin sulfate proteoglycans are major inhibitory molecules for neural plasticity under both physiological and pathological conditions. The chondroitin sulfate degrading enzyme chondroitinase ABC promotes functional recovery after spinal ...
R. Tauchi, S. Imagama, Takamitsu Natori, Tomohiro Ohgomori, Akio Muramoto, R. Shinjo, Y. Matsuyama, N. Ishiguro, K. Kadomatsu   +8 more
semanticscholar   +1 more source

Heparan sulfate and cell division

Brazilian Journal of Medical and Biological Research, 1999
Heparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic ...
Porcionatto M.A., Nader H.B., Dietrich C.P.   +2 more
doaj  

Proteoglycans as Therapeutic Targets in Brain Cancer

Frontiers in Oncology, 2020
Proteoglycans (PGs) are heavily glycosylated diverse proteins consisting of a “core protein” covalently attached to glycosaminoglycans (GAGs) and present on the cell surface, extracellular matrix, and intracellular milieu.
Zoya Yan, Shanzhi Wang
doaj   +1 more source

Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis*

Journal of Biological Chemistry, 2012
Background: In atherosclerosis, proteoglycan accumulation results in increased lipoprotein retention. Results: ADAMTS-5 is reduced in aortas of apolipoprotein E-null mice.
A. Didangelos, U. Mayr, C. Monaco, M. Mayr   +3 more
semanticscholar   +1 more source

Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution

Frontiers in Cell and Developmental Biology, 2020
Efficient cell migration requires cellular polarization, which is characterized by the formation of leading and trailing edges, appropriate positioning of the nucleus and reorientation of the Golgi apparatus and centrosomes toward the leading edge ...
Daniel Becsky, Kitti Szabo, Szuzina Gyulai-Nagy, Tamas Gajdos, Zsuzsa Bartos, Arpad Balind, Laszlo Dux, Peter Horvath, Miklos Erdelyi, Laszlo Homolya, Aniko Keller-Pinter   +10 more
doaj   +1 more source

The proteoglycan bikunin has a defined sequence

Nature Chemical Biology, 2011
Proteoglycans are complex glycoconjugates that regulate critical biological pathways in all higher organisms. Bikunin, the simplest proteoglycan having a single glycosaminoglycan chain, is a serine protease inhibitor used to treat acute pancreatitis ...
Mellisa Ly, F. E. Leach, Tatiana N. Laremore, T. Toida, I. Amster, Robert J. Linhardt   +5 more
semanticscholar   +1 more source