Results 91 to 100 of about 114,169 (274)

Conservation of core complex subunits shaped the structure and function of photosystem I in the secondary endosymbiont alga Nannochloropsis gaditana [PDF]

, 2017
Photosystem I (PSI) is a pigment protein complex catalyzing the light-driven electron transport from plastocyanin to ferredoxin in oxygenic photosynthetic organisms.
Alboresi, Alessandro Alboresi, Allen, Andrea Meneghesso, Archibald, Basso, Ben-Shem, Bernal-Bayard, Boekema, Boekema, Bondioli, Busch, Busch, Busch, Castelletti, Caterina Gerotto, Cavalier-Smith, Clotilde Le Quiniou, Corteggiani Carpinelli, Cox, Croce, Croce, Croce, Diana Simionato, Drop, Drop, Egbert J. Boekema, Engelmann, Färber, Gardian, Geer, Gobets, Gobets, Grouneva, Haldrup, Ikeda, Jansson, Jennings, Jensen, Jensen, Jordan, Khrouchtchova, Kouril, Kouril, Le Corguillé, Le Quiniou, Le Quiniou, Li, Litvín, Liu, Lunde, Martin Scholz, Mazor, Michael Hippler, Morosinotto, Mozzo, Nelson, Oostergetel, Palacios, Passarini, Passarini, Qin, Raven, Riisberg, Roberta Croce, Rodolfi, Sathish K. N. Yadav, Scheres, Scheres, Schmid, Shevchenko, Simionato, Snellenburg, Starkenburg, Sukenik, Sukenik, Terashima, Thangaraj, Tomas Morosinotto, van Stokkum, Vanselow, Veith, Vieler, Watanabe, Watanabe, Wientjes, Wientjes, Wientjes   +87 more
core   +3 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Bacterial protein meta-interactomes predict cross-species interactions and protein function [PDF]

, 2017
Background Protein-protein interactions (PPIs) can offer compelling evidence for protein function, especially when viewed in the context of proteome-wide interactomes.
Caufield, J. Harry, Shary, Semarjit, Uetz, Peter, Wimble, Christopher, Wuchty, Stefan   +4 more
core   +1 more source

Quantitative tandem affinity purification, an effective tool to investigate protein complex composition in plant hormone signaling : strigolactones in the spotlight [PDF]

, 2018
Phytohormones tightly regulate plant growth by integrating changing environmental and developmental cues. Although the key players have been identified in many plant hormonal pathways, the molecular mechanisms and mode of action of perception and ...
Boyer, François-Didier, Braem, Lukas, De Jaeger, Geert, De Keyser, Annick, Gevaert, Kris, Goormachtig, Sofie, Persiau, Geert, Struk, Sylwia Magdalena, Walton, Alan   +8 more
core   +2 more sources

Sex‐Specific Causal Genes for Alzheimer’s Disease via Proteome‐Wide Association Studies

Alzheimer's & Dementia
AbstractBackgroundWomen are at higher risk of developing Alzheimer’s disease (AD). Sex differences in AD pathobiology and prevalence appear to be partially attributed to genetics, but sex‐stratified genome‐wide association studies (GWAS) of AD have demonstrated a relative paucity of associated variants, which may reflect challenges of limited power ...
Reid, Danielle M., Belloy, Michael E.
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Integrative analysis of the colorectal cancer proteome : potential clinical impact [PDF]

, 2016
Peer ...
Alnabulsi, Abdo, Murray, Graeme I.
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]

, 2015
Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro, Onwuli, Donatus O.   +1 more
core   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source