A synergistic multi-omics approach: causal sepsis drivers identified in activated CD4<sup>+</sup> T cells by single-cell RNA sequencing and Mendelian randomization. [PDF]
Front Cell Infect MicrobiolZhou J +6 more
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Veterinary Dermatology, EarlyView.Background: Contagious ecthyma (Orf) is a highly contagious, economically significant disease affecting sheep, goats and wild small ruminants, caused by the resilient Orf virus (ORFV). It produces thick, crusted lesions around the mouth and nostrils, especially in animals aged 3–4 months, sometimes causing near 100% mortality in immunocompromised young
Emine Nur Dincer, Ozlem Ozmen
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Ketone-Dependent Restoration of Autophagy and Mitochondrial Quality Control Through VPS35 in a Drosophila Model of C99-Induced Neurodegeneration. [PDF]
CellsHuang H, Xu K, Lardellia M.
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Redefining Endometrial Decidualization: The Central Role of the ER Stress-Immune-Metabolic Axis. [PDF]
Int J Mol SciKaraoğlan Ö, Tap Ö, Ürünsak İF.
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The proteostasis paradox: from systemic collapse in aging to pathway-specific addiction in prostate cancer. [PDF]
Front Cell Dev BiolGuo D, Peng Y, Yu Y.
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Isoflurane aggravates pre-existing proteotoxicity in adult nematodes by suppressing mitochondrial fitness. [PDF]
Sci RepElami T +7 more
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Biomolecular mechanisms of cardiac amyloidosis and its cardiovascular pathological basis. [PDF]
Front ImmunolZhang L, Jiao Y, Guo J.
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Correction Paschou et al., Dysregulated proteostasis in p.A53T-α-Synuclein astrocytes aggravates Lewy-like neuropathology in a Parkinson's disease iPSC model. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +1 more source