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2023
Proteostasis, the control of all aspects of assembly, turnover and removal of proteins within the cellular proteome by a proteostasis network of ∼2000 proteins present in all tissues, is achieved through both acute, nutritionally-sensitive, within tissue mechanisms, throughout the diurnal-cycle of feeding and fasting and through more long-term, between-
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Proteostasis, the control of all aspects of assembly, turnover and removal of proteins within the cellular proteome by a proteostasis network of ∼2000 proteins present in all tissues, is achieved through both acute, nutritionally-sensitive, within tissue mechanisms, throughout the diurnal-cycle of feeding and fasting and through more long-term, between-
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Proteostasis in neurodegenerative diseases
Proteostasis is essential for normal function of proteins and vital for cellular health and survival. Proteostasis encompasses all stages in the "life" of a protein, that is, from translation to functional performance and, ultimately, to degradation. Proteins need native conformations for function and in the presence of multiple types of stress, their ...Sumit, Kinger +8 more
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2020
Proteostasis regulates key cellular processes such as cell proliferation, differentiation, transcription, and apoptosis. The mechanisms by which proteostasis is regulated are crucial and the deterioration of cellular proteostasis has been significantly associated with tumorigenesis since it specifically targets key oncoproteins and tumor suppressors ...
Erbaykent Tepedelen, Burcu +3 more
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Proteostasis regulates key cellular processes such as cell proliferation, differentiation, transcription, and apoptosis. The mechanisms by which proteostasis is regulated are crucial and the deterioration of cellular proteostasis has been significantly associated with tumorigenesis since it specifically targets key oncoproteins and tumor suppressors ...
Erbaykent Tepedelen, Burcu +3 more
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Defective proteostasis in Alzheimer’s disease
Ageing Research Reviews, 2023Felipe C Ribeiro, Sérgio T Ferreira
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Stress-responsive regulation of extracellular proteostasis
Journal of Cell Biology, 2022Jaleh S Mesgarzadeh +2 more
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Chloroplast proteostasis: A story of birth, life, and death
Plant Communications, 2023Guo-Zhang Wu
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Mechanisms Linking Mitochondrial Dysfunction and Proteostasis Failure
Trends in Cell Biology, 2020Bingwei Lu, Su Guo
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