An automated plasma-based proteotyping immunoassay for APOE ε4 zygosity classification in Alzheimer's disease. [PDF]
Alzheimers DementAbstract INTRODUCTION Determining apolipoprotein E (APOE) ε4 allele status, a key genetic risk factor for Alzheimer's disease (AD), requires molecular genotyping infrastructure not widely accessible beyond specialized centers. METHODS A fully automated high‐throughput apoE E4 proteotyping immunoassay was evaluated for clinical performance (460 ...
Levin S +15 more
europepmc +2 more sources
Evaluation of Two Plasma-Based Proteotyping Assays Against APOE ε4 Genotyping in a Memory Clinic Setting: The Gothenburg H70 Clinical Studies [PDF]
Alzheimer's and DementiaAndrea L Benedet +2 more
exaly +2 more sources
Salivary proteotypes of gingivitis tolerance and resilience [PDF]
Journal of Clinical Periodontology, 2020 AbstractAimThis study aimed to characterize the salivary proteome during the induction and resolution of gingival inflammation in the course of human experimental gingivitis (EG), and to cluster the proteomic profiles based on the clinically defined “slow” and “fast” response patterns.Materials and MethodsA total of 50 unstimulated whole saliva were ...
Nagihan Bostanci +8 more
openaire +4 more sources
Universal Identification of Pathogenic Viruses by Liquid Chromatography Coupled With Tandem Mass Spectrometry Proteotyping [PDF]
Molecular and Cellular ProteomicsJean Armengaud +2 more
exaly +2 more sources
Reproducible Determination of High-Density Lipoprotein Proteotypes
Journal of Proteome Research, 2021 Journal of Proteome Research, 20 (11)
Goetze, Sandra +9 more
openaire +3 more sources
Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals [PDF]
Cell, 2019 ISSN:0092 ...
Romanov, Natalie +5 more
openaire +5 more sources
Frontiers in Microbiology, 2022 Microorganisms proteotyping by tandem mass spectrometry has been recently shown as a powerful methodology to identify the wide-range taxonomy and biomass of microbiota.
Pauline Hardouin +7 more
doaj +1 more source
Matrix-assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Can Precisely Discriminate the Lineages of Listeria monocytogenes and Species of Listeria. [PDF]
PLoS ONE, 2016 The genetic lineages of Listeria monocytogenes and other species of the genus Listeria are correlated with pathogenesis in humans. Although matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has become a ...
Teruyo Ojima-Kato +3 more
doaj +1 more source
Survival proteomes: the emerging proteotype of antimicrobial resistance [PDF]
FEMS Microbiology Reviews, 2016 Antimicrobial resistance is one of the greatest challenges in modern medicine. Infectious diseases that have historically been eliminated with routine antibiotic therapy are now re-emerging as life threatening illnesses. A better understanding of the specific mechanisms that contribute to resistance are required to optimize the treatment of infectious ...
Amber J, Park +2 more
openaire +2 more sources
Proteotypic Differences of Follicular-Patterned Thyroid Neoplasms
Frontiers in Endocrinology, 2022 The diagnosis of follicular-patterned thyroid tumors such as follicular thyroid adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains challenging. This study aimed to explore the molecular differences among these three thyroid tumors by proteomic analysis.
Dongdong Huang +25 more
openaire +3 more sources