Results 91 to 100 of about 174,020 (338)

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, EarlyView.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Amelia Goddard, Emma H. Hooijberg   +2 more
wiley   +1 more source

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo, Liumbruno, Giancarlo Maria, Marano, Giuseppe, Mengoli, Carlo, Piccinini, Vanessa, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Human prothrombin activation

Journal of Biological Chemistry, 1975
Human prothrombin has been purified from American Red Cross Factor IX concentrates. Studies of the activation of the human prothrombin with the use of sodium dodecyl sulfate electrophoretic analysis of activation products indicated that human prothrombin activation is similar to bovine prothrombin activation.
M R, Downing, R J, Butkowski, M M, Clark, K G, Mann   +3 more
openaire   +2 more sources

Common Variations in Prothrombotic Genes and Susceptibility to Ischemic Stroke in Young Patients: A Case-Control Study in Southeast Iran

Medicina, 2019
Background and Objective: Evidence indicates that genetic factors may be involved in the risk of ischemic stroke (IS). The aim of this study was to assess the effect of genetic polymorphisms located in exons or untranslated regions of MTHFR as well as FV
Seyed Mehdi Hashemi, Nourollah Ramroodi, Hamed Amiri Fard, Sahar Talebian, Maryam Haghighi Rohani, Mahnaz Rezaei, Mehrangiz Noora, Saeedeh Salimi   +7 more
doaj   +1 more source

Prothrombin Time, an Indicator for Psoriasis Activity: A Case - Control Study

Iranian South Medical Journal, 2020
Background: Psoriasis is a common chronic and recurrent inflammatory skin disorder related to the immune system and characterized by the rapid growth of skin cells.
Majid Morovati-Sharifabad, Maryam Yahyaie, Elham Salehi   +2 more
doaj  

Frequency of Factor V Leiden and Prothrombin Polymorphism in South of Iran [PDF]

Iranian Journal of Medical Sciences, 2009
Normal hemostasis requires balanced regulation of prothromboticand antithrombotic factors. Inherited alteration of factor Vand prothrombin gene, the G20210A mutation, increases the resistanceof factor V to degradation and booster production ofprothrombin
Javad Dehbozorgian, Abdolreza Afrasiabi, Majid Yavarian, Golam Reza Panahandeh Shahraki, Mehran Karimi, Mohammadreza Bordbar, Pier M. Mannucci   +6 more
doaj  

Homozygous prothrombin gene mutation and ischemic cerebrovascular disease: A case report and review of literature

Journal of Applied Hematology, 2019
This report describes a 32-year-old Saudi nonsmoker man who presented to the emergency department with a history of left-sided hemiparesis and no risk factors for cerebral stroke being reported, except type II diabetes mellitus.
Mohammed AlSheef, Mohammed S Almohaya, Arshad M Mian, Saad Mohammed Aljuhayyim   +3 more
doaj   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi, Michail Kalinderis, Maria Chatzidimitriou, Liana Fidani   +3 more
wiley   +1 more source

A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

Clinical Case Reports
Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant.
Cecilia Augustsson, Knut Taxbro, Karin Strandberg, Eva Zetterberg   +3 more
doaj   +1 more source

Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression [PDF]

, 2004
<p><b>Background and Purpose:</b> Early clinical progression of ischemic stroke is common and is associated with increased risk of death and dependency.
Barber, M., Langhorne, P., Lowe, G.D.O., Rumley, A., Stott, D.J.   +4 more
core   +1 more source