Results 101 to 110 of about 145,714 (241)

Systemic lupus erythematosus‐associated autoantibodies in sickle cell disease: Spontaneous emergence in a patient and in transgenic sickle mice

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1213-1217, April 2025.
Summary We describe a patient with sickle cell disease (SCD) and elevated antiphospholipid antibodies (aPL) who developed multi‐organ failure resembling catastrophic antiphospholipid syndrome. Autoimmune screening revealed several autoantibodies characteristic of systemic lupus erythematosus (SLE). Notably, routinely housed and unmanipulated transgenic
Urshita Sinha   +8 more
wiley   +1 more source

Production and Functional Verification of 8‐Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)‐Edited Donor Pigs for Xenotransplantation

open access: yesCell Proliferation, EarlyView.
Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang   +23 more
wiley   +1 more source

Coagulation disorders after reperfusion of pancreatic allografts [PDF]

open access: yes, 1993
Blumenstock, I.   +5 more
core   +1 more source

Quantitative proteomics identifies plasma protein alterations that associate with metabolic and thrombotic profile changes after bariatric surgery

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2647-2657, May 2025.
Abstract Objective Roux‐en‐Y gastric bypass (RYGB) surgery has been shown to lead to favourable health outcomes in obese patients. However, the molecular changes that occur and how they relate to clinical measures are poorly understood. Here, we characterise the proteomic alterations that occur in plasma of RYGB patients before and 9 months after ...
Hasnain Ahmed   +6 more
wiley   +1 more source

Mid‐regional pro‐adrenomedullin: A rapid sepsis biomarker for diagnosing spontaneous bacterial peritonitis in cirrhosis

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 6, June 2025.
The study design included a derivation cohort of 236 visits and a validation cohort of 85 visits. Patients with cirrhosis and ascitic decompensation were evaluated and categorized based on the presence or absence of bacteriologically confirmed‐spontaneous bacterial peritonitis (BC‐SBP).
Abderrahim Oussalah   +17 more
wiley   +1 more source

The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou   +10 more
wiley   +1 more source

Immune Tolerance Induction With a Recombinant Factor VIII Fc in Haemophilia A: Data From a Chart Review Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objective To report data from an ITI chart review study (NCT03951103) for first‐time and rescue ITI with recombinant factor VIII Fc fusion protein (rFVIIIFc) in persons with haemophilia A. Methods Retrospective and prospective real‐world data are reported from a non‐interventional, multicentre study of patients who had been or were currently ...
Robert Klamroth   +7 more
wiley   +1 more source

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