Results 61 to 70 of about 105,223 (244)

Hemostatic abnormalities at the time of fetal death: A retrospective study evaluating the prevalence and relevance of targeted testing

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the prevalence of hemostasis abnormalities at the time of fetal death diagnosis. Methods This retrospective single‐center study included all fetal deaths between 22 and 42 weeks from July 2017 to December 2023, excluding multiple pregnancies, patients on anticoagulant therapy, and those with known pre‐existing coagulation ...
Chloé Lieng, Catherine Fischer, Aude Girault   +2 more
wiley   +1 more source

The frequency of β-globin gene haplotypes, α-thalassemia and genetic polymorphisms of methylenetetrahydrofolate reductase, factor V Leiden and prothrombin genes in children with sickle cell disease in Rio de Janeiro, Brazil Frequência dos haplótipos da globina beta, da talassemia alfa e dos polimorfismos genéticos dos genes da metilenotetrahidrofolato redutase, do fator V Leiden e da protrombina em crianças com doença falciforme no Rio de Janeiro, Brasil

Revista Brasileira de Hematologia e Hemoterapia, 2010
A freqüência dos haplótipos beta S e beta C do gene da globina e a prevalência de talassemia alfa e de mutações nos genes da metilenotetrahidrofolato redutase (MTHFR-C677T), do fator V de Leiden e da protrombina (G20210A) foi estudada em crianças com ...
Isaac L. Silva Filho, Georgina S. Ribeiro, Leíse M. Pimenta-Bueno, Maria José A. Serpa   +3 more
doaj   +1 more source

Human prothrombin activation

Journal of Biological Chemistry, 1975
Human prothrombin has been purified from American Red Cross Factor IX concentrates. Studies of the activation of the human prothrombin with the use of sodium dodecyl sulfate electrophoretic analysis of activation products indicated that human prothrombin activation is similar to bovine prothrombin activation.
M R, Downing, R J, Butkowski, M M, Clark, K G, Mann   +3 more
openaire   +2 more sources

Prescription trends for combined oral contraceptives and thromboembolism incidence in Japan before and after public awareness events in 2013–2015

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Combined oral contraceptives (COCs) for dysmenorrhea management have been covered by the Japanese universal health insurance system since 2008. Several public awareness events regarding COC prescriptions for dysmenorrhea were implemented between 2013 and 2015, including media reports on COC‐related fatalities in 2013, drug safety ...
Risa Ishida, Yusuke Sasabuchi, Kaori Koga, Shiori Itoi, Gentaro Izumi, Daisuke Shigemi, Hiroki Matsui, Yutaka Osuga, Hideo Yasunaga   +8 more
wiley   +1 more source

A Machine Learning Model Based on Blood Indices for the Differential Diagnosis of Colorectal Cancer and Colorectal Polyps

iLABMED, EarlyView.
This diagram systematically sorts out the complete data processing pipeline, clearly presenting the key links and logical connections from raw data collection, preprocessing (including cleaning, deduplication, format standardization, etc.), and core computational analysis to the result output.
Wenhui Yan, Lin Zhu, Hongming Wei, Jie Feng, Yanhong Gao   +4 more
wiley   +1 more source

Coagulation state monitoring of burn patients in Duhok governorate, Iraq

Indian Journal of Burns
Background and Objective: Patients with severe burns have coagulation abnormalities that are similar to those seen in sepsis or acute trauma patients. Patients with severe burns who experience coagulopathy exhibit abnormalities in procoagulants as well ...
Beri Adil Tawfeq, Bizav Naji Rasheed
doaj   +1 more source

Construction and Validation of a Preoperative Surgical Difficulty Prediction and Risk Stratification System for Posterior Spinal Deformity Correction Surgery Based on Machine Learning ‐ Multicenter Cohort Study

iMetaMed, EarlyView.
A web calculator, trained on multicenter data with seven Boruta‐selected preoperative features, predicts prolonged operative time for posterior spinal deformity correction to enable individualized planning and optimized operating‐room resources. ABSTRACT Operative duration reflects surgical complexity and is valuable for perioperative planning.
Chan Xu, Jialiang Zheng, Chengliang Yin, Runmin Li, Xubin Quan, Binghao Chen, Zhaohui Hu, Tongqing Luo, Hao Jiang, Xuewen Hou, Qizhong Xu, Weiheng He, Liang Chen, Anfa Chen, Xin Zhou, Wei Huang, Sen Gao, Jiali Yu, Zhi‐Ri Tang, Yusi Zhang, Kai Wang, Shi‐Nan Wu, Wencai Liu, Xiangdong Xi, Haizhen Ding, Qiang Liu, Haopeng Luan, Wenle Li   +27 more
wiley   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source

Flow Cytometric Profiling Reveals Platelet Dysfunction and Impaired Immune Communication in Acute and Chronic Cerebrovascular Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Platelets act as sensors linking inflammation and neurovascular health. Flow cytometry revealed reduced PAC‐1 in acute/subacute ICH but elevated in chronic disease, while P‐selectin remained suppressed. T lymphocyte–platelet aggregates declined across groups, indicating disrupted immune crosstalk, and these biomarkers reflect stage‐specific platelet ...
Chih‐Lung Shen, Li‐Yu Huang, Jhong‐Kuei Chen, Sheng‐Tzung Tsai, Yi‐feng Wu   +4 more
wiley   +1 more source

Prevalence of hereditary risk factors for thrombophilia in Belém, Brazilian Amazon

Genetics and Molecular Biology, 2006
Different risk factors for venous thromboembolism (VTE) have been identified, including hereditary abnormalities in the mechanisms of coagulation and fibrinolysis.
France Keiko Nascimento Yoshioka, Amélia Góes Araújo, Marli Haydee Tavella, Igor Guerreiro Hamoy, João Farias Guerreiro   +4 more
doaj   +1 more source