Results 61 to 70 of about 145,714 (241)
ABSTRACT Background COVID‐19 can affect hematological and biochemical parameters, potentially altering platelet function. This study aimed to evaluate the long‐term effects of COVID‐19 on the quality of platelet concentrates (PCs) collected from donors with a history of infection.
Fatemeh Arastehnazar+4 more
wiley +1 more source
Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez+8 more
wiley +1 more source
Drug‐induced liver injury associated with exposure to Hangeshashinto
While Kampo medicines are deemed relatively safe and associated with few adverse effects, primary care physicians are well advised to be aware of the risk of drug‐induced liver injury in patients prescribed Kampo medicines containing Scutellariae radix, such as Hangeshashinto, in clinical practice and to closely monitor their clinical course.
Kimitoshi Kubo+2 more
wiley +1 more source
An infant with Kawasaki disease having gastrointestinal bleeding due to multiple gastric ulcers
Abstract Kawasaki disease (KD) is an acute systemic vasculitis managed mainly through intravenous immunoglobulin (IVIG), aspirin, and steroids. Although gastrointestinal symptoms are common, gastrointestinal bleeding is rare. We present the case of an 11‐month‐old girl with incomplete KD who developed severe gastrointestinal bleeding due to multiple ...
Takeru Kanazawa+3 more
wiley +1 more source
Comparative frequency of Coagulation Factor II and Coagulation Factor V Alleles among new-born and senior citizens [PDF]
Resistance to activated protein C is one of the most common inherited disorders associated with hereditary thrombophilia. A missense mutation in the gene coding for coagulation factor V (CF V Leiden) and which renders this procoagulant factor resistant ...
Abela Medici, Joseph+4 more
core
SummaryThe prothrombin activation cycle consists of a sequence described by the following: Prothrombin (sensitive to calcium + Ac-globulin + lung thromboplastin) → Prothrombin derivative I (not sensitive to calcium + Ac-globulin + lung thromboplastin) → Prothrombin derivative II (sensitive to calcium + Ac-globulin + lung thromboplastin) → Thrombin ...
Walter H. Seegers, Min H. Cho
openaire +3 more sources
ABSTRACT Background The Japanese Society of Hepatobiliary and Pancreatic Surgery has established a certification system for experienced surgeons. Evaluating its efficacy requires accounting for patient risk variations. The National Clinical Database (NCD) facilitates this using risk‐adjusted outcome measures to validate and compare surgical performance.
Takayuki Anazawa+6 more
wiley +1 more source
Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta+8 more
wiley +1 more source
In many medical studies, patients are followed longitudinally and interest is on assessing the relationship between longitudinal measurements and time to an event.
Albert, Paul S., Shih, Joanna H.
core +1 more source