Results 71 to 80 of about 145,714 (241)

Thromboelastography Maximum Amplitude Is a Valuable Biomarker for Early Atherosclerosis in Rheumatoid Arthritis Patients: A Single‐Center Cross‐Sectional Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hypercoagulability contributes to atherosclerosis (AS) progression in individuals suffering from rheumatoid arthritis (RA), and thromboelastography (TEG) is a valuable diagnostic tool. This hospital‐based cross‐sectional study assessed the clinical efficacy of TEG parameters in detecting hypercoagulability and subclinical AS by purposively ...
Qing‐Lin Zhang   +6 more
wiley   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra   +3 more
wiley   +1 more source

Electrophoresis of Prothrombin

open access: yesExperimental Biology and Medicine, 1944
SummaryThe electrophoretic mobility of bovine prothrombin is greater than that of the more concentrated plasma protein constituents. At pH 7, heparin does not alter the mobility of prothrombin. The isoelectric point of prothrombin is in the region of pH 4.8 and in all probability is identical with the inactivation point.
Eugene C. Loomis   +2 more
openaire   +2 more sources

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall   +25 more
wiley   +1 more source

Risk Factors and Clinical Features of Deterioration in 739 COVID‐19 Affected Children Aged Under 14 Years in Zhuhai, China: A Multicenter, Retrospective Study

open access: yesPediatric Discovery, EarlyView.
Seven hundred and thirty‐nine children infected with SARS‐CoV‐2 in Zhuhai tend to have close‐contact aggregated morbidity within the family, with fever and cough as the main manifestations. Low age, underlying disease, some laboratory indicators, and patchy exudative changes on CT of the lungs are the windsocks of the severity of the infection ...
Ting Liu   +7 more
wiley   +1 more source

The role of rehabilitation across the continuum of liver disease from cirrhosis to transplantation and beyond: A narrative review

open access: yesPM&R, EarlyView.
Abstract Objective The authors' objective with this narrative review is to explore the impact of rehabilitative interventions at each stage of liver disease. Type Narrative review. Literature Survey Literature search conducted in Medline, Embase, and Google Scholar databases.
Laura Malmut   +5 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

Prothrombin and Haemorrhage [PDF]

open access: yesBMJ, 1954
Anne C. Donald   +4 more
openaire   +3 more sources

Multiple Concomitant Precipitating Factors of Hepatic Encephalopathy Are Associated With a Poor Prognosis in Patients With Cirrhosis Admitted to Intensive Care Unit

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Management of hepatic encephalopathy relies on the identification and control of precipitating factors (PF). The prognostic value of a PF is unknown, which we aimed to explore. Patients and Methods Single‐center retrospective study of cirrhotic patients included in a prospective cohort admitted to an intensive care unit (ICU ...
Marika Rudler   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy