Results 91 to 100 of about 6,958 (184)

A phase separation hypothesis for the biological function of PrP: the role of multivalent interactions at the plasma membrane. [PDF]

Biochem Soc Trans
Freire MH, Linden R, Cordeiro Y.
europepmc   +1 more source

Genome-wide screens identify core regulators of cell surface prion protein expression. [PDF]

Sci Rep
Beauchemin KS, Supattapone S.
europepmc   +1 more source

PrP^C-Neutralizing Antibody Confers an Additive Benefit in Combination with 5-Fluorouracil in KRAS-Mutant Colorectal Cancer Models, Associated with Reduced RAS-GTP and AKT/ERK Phosphorylation. [PDF]

Int J Mol Sci
Lee JK, Yoon JY, Lee JY, Lee SH.
europepmc   +1 more source

Oligosaccharyltransferase (OST) complex inhibition effectively treats rodent and human prions. [PDF]

PLoS Pathog
Beauchemin KS, Kun J, Groveman B, Williams K, Salerno F, Francomacaro LM, Robison P, Haigh CL, Supattapone S.   +8 more
europepmc   +1 more source

Membrane-anchored PrPSc is the trigger for prion synaptotoxicity. [PDF]

PLoS Pathog
Gatdula JRP, Mercer RCC, Alepuz Guillen JA, Vultaggio JS, Harris DA.   +4 more
europepmc   +1 more source

Cellular Prion Protein (PrPC): Identification and Characterization of Novel Interacting Partners [PDF]

, 2022
openaire   +1 more source

Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates. [PDF]

Cell Biosci
Bigi A, Conti AC, Napolitano L, Fusco G, De Simone A, Chiti F, Cascella R, Cecchi C.   +7 more
europepmc   +1 more source

Refined Transgenic Mouse Models Which Recapitulate the Natural Features of Chronic Wasting Disease With Rapid Prion Disease Onsets. [PDF]

J Infect Dis
DeFranco JP, Kim S, Atkinson ZN, Crowell J, Lei S, Bian J, Telling GC.   +6 more
europepmc   +1 more source

Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains. [PDF]

Proc Natl Acad Sci U S A
DeFranco JP, Bian J, Kim S, Atkinson ZN, Crowell J, Kang HE, Bodrogi HO, Christiansen JR, Díaz-Domínguez CM, Telling GC.   +9 more
europepmc   +1 more source

Mutant knock-in mice display enhanced susceptibility to pure prion protein fibrils. [PDF]

J Gen Virol
Walsh DJ, Standke H, Kraus A, Watts JC, Supattapone S.   +4 more
europepmc   +1 more source